A single-blinded, randomized pilot study of botulinum toxin type A combined with non-pharmacological treatment for spastic foot.

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State: Public
Version: Final published version
License: Not specified
Serval ID
serval:BIB_6246128D46AE
Type
Article: article from journal or magazin.
Collection
Publications
Title
A single-blinded, randomized pilot study of botulinum toxin type A combined with non-pharmacological treatment for spastic foot.
Journal
Journal of Rehabilitation Medicine : Official Journal of the Uems European Board of Physical and Rehabilitation Medicine
Author(s)
Baricich A., Carda S., Bertoni M., Maderna L., Cisari C.
ISSN
1651-2081 (Electronic)
ISSN-L
1650-1977
Publication state
Published
Issued date
2008
Peer-reviewed
Oui
Volume
40
Number
10
Pages
870-872
Language
english
Notes
Publication types: Comparative Study ; Journal Article ; Randomized Controlled Trial Publication Status: ppublish
Abstract
OBJECTIVE: To explore the effect of treatment after botulinum toxin type A combined with treatments for the spastic foot.
DESIGN: Single-blind, randomized trial, with 3-month follow-up.
SUBJECTS: Twenty-three chronic hemiplegic adult patients with spastic equinus foot.
METHODS: Following botulinum toxin type A injection at the medial and lateral gastrocnemius, patients were assigned randomly to 3 groups, and treated with taping, electrical stimulation or stretching. They were evaluated before treatment (t0), and at 10 (t1), 20 (t2) and 90 (t3) days after treatment. Outcome measures were: Modified Ashworth Scale; passive range of motion at the ankle; measurement of muscle action potential at the gastrocnemius medialis; and measurement of maximum ankle dorsiflexion angle in stance using gait analysis.
RESULTS: The group treated with electrical stimulation performed better at t1 on the Modified Ashworth Scale. The taping and electrical stimulation groups performed better in all outcome measures at t3. The taping group performed better mainly for maximum ankle dorsiflexion angle in stance. The stretching group showed a less durable result, with some worsening at the t3 evaluation compared with the assessment performed before treatment.
CONCLUSIONS: This pilot study indicates that combining botulinum toxin type A administration for the ankle plantar flexors with taping and electrical stimulation might be beneficial.
Keywords
Adult, Aged, Bandages, Botulinum Toxins, Type A/administration & dosage, Botulinum Toxins, Type A/therapeutic use, Electric Stimulation Therapy, Female, Follow-Up Studies, Foot/physiopathology, Gait Disorders, Neurologic/drug therapy, Gait Disorders, Neurologic/physiopathology, Hemiplegia/etiology, Hemiplegia/physiopathology, Humans, Male, Middle Aged, Muscle Spasticity/drug therapy, Muscle Spasticity/physiopathology, Muscle Stretching Exercises, Neuromuscular Agents/administration & dosage, Neuromuscular Agents/therapeutic use, Pilot Projects, Range of Motion, Articular, Splints, Stroke/complications, Stroke/physiopathology, Treatment Outcome
Pubmed
Open Access
Yes
Create date
25/03/2013 17:21
Last modification date
15/07/2020 5:26
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