Macrophage migration inhibitory factor is a neuroendocrine mediator of endotoxaemia

Details

Serval ID
serval:BIB_6242AA8F6505
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Macrophage migration inhibitory factor is a neuroendocrine mediator of endotoxaemia
Journal
Trends in Microbiology
Author(s)
Bernhagen  J., Calandra  T., Cerami  A., Bucala  R.
ISSN
0966-842X (Print)
Publication state
Published
Issued date
06/1994
Volume
2
Number
6
Pages
198-201
Notes
Journal Article
Review --- Old month value: Jun
Abstract
The cytokine macrophage migration inhibitory factor (MIF) is a major protein constituent of the anterior pituitary gland released into the bloodstream during endotoxaemia. For many years, MIF had been thought to be a T cell product associated with delayed-type hypersensitivity reactions. The identification of MIF as a pituitary 'stress' hormone provides an important link in the regulation of systemic inflammatory responses by the central nervous system.
Keywords
Animals Bacterial Infections/blood/*metabolism Endotoxins/*blood Humans Macrophage Migration-Inhibitory Factors/*physiology Macrophages/metabolism Mice Pituitary Gland/*metabolism
Pubmed
Create date
25/01/2008 14:28
Last modification date
20/08/2019 15:19
Usage data