How to assess prognosis after cardiac arrest and therapeutic hypothermia.

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Ressource 1Download: BIB_619F9E06C1EC.P001.pdf (2397.71 [Ko])
State: Public
Version: author
Serval ID
serval:BIB_619F9E06C1EC
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
How to assess prognosis after cardiac arrest and therapeutic hypothermia.
Journal
Critical Care
Author(s)
Taccone F., Cronberg T., Friberg H., Greer D., Horn J., Oddo M., Scolletta S., Vincent J.L.
ISSN
1466-609X (Electronic)
ISSN-L
1364-8535
Publication state
Published
Issued date
2014
Peer-reviewed
Oui
Volume
18
Number
1
Pages
202
Language
english
Notes
Publication types: Journal Article, pdf :Review
Abstract
The prognosis of patients who are admitted in a comatose state following successful resuscitation after cardiac arrest remains uncertain. Although the introduction of therapeutic hypothermia (TH) and improvements in post-resuscitation care have significantly increased the number of patients who are discharged home with minimal brain damage, short-term assessment of neurological outcome remains a challenge. The need for early and accurate prognostic predictors is crucial, especially since sedation and TH may alter the neurological examination and delay the recovery of motor response for several days. The development of additional tools, including electrophysiological examinations (electroencephalography and somatosensory evoked potentials), neuroimaging and chemical biomarkers, may help to evaluate the extent of brain injury in these patients. Given the extensive literature existing on this topic and the confounding effects of TH on the strength of these tools in outcome prognostication after cardiac arrest, the aim of this narrative review is to provide a practical approach to post-anoxic brain injury when TH is used. We also discuss when and how these tools could be combined with the neurological examination in a multimodal approach to improve outcome prediction in this population.
Pubmed
Web of science
Open Access
Yes
Create date
15/12/2014 16:52
Last modification date
20/08/2019 14:18
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