False-negative PCR result due to gene polymorphism: the example of Neisseria meningitidis.

Details

Serval ID
serval:BIB_6161402352BF
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Institution
Title
False-negative PCR result due to gene polymorphism: the example of Neisseria meningitidis.
Journal
Journal of Clinical Microbiology
Author(s)
Jaton Katia, Ninet Beatrice, Bille Jacques, Greub Gilbert
ISSN
1098-660X[electronic], 0095-1137[linking]
Publication state
Published
Issued date
2010
Volume
48
Number
12
Pages
4590-4591
Language
english
Abstract
Early treatment of meningococcal meningitis is mandatory but may negate the cerebrospinal fluid culture. Etiological diagnosis then mainly relies on PCR. Here, we report a case of false-negative results for real-time PCR for a Neisseria meningitidis serogroup B isolate with a polymorphism in the ctrA gene.
Keywords
Real-Time PCR, Acid Amplification Tests, Streptococcus-Pneumoniae, Haemophilus-Influenzae, Diagnosis, Identification, Mitis
Pubmed
Web of science
Create date
20/12/2010 11:21
Last modification date
20/08/2019 15:18
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