Oral Terbinafine and Itraconazole Treatments against Dermatophytes Appear Not to Favor the Establishment of Fusarium spp. in Nail.

Details

Serval ID
serval:BIB_6093BD963633
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Oral Terbinafine and Itraconazole Treatments against Dermatophytes Appear Not to Favor the Establishment of Fusarium spp. in Nail.
Journal
Dermatology
Author(s)
Verrier J., Bontems O., Baudraz-Rosselet F., Monod M.
ISSN
1421-9832 (Electronic)
ISSN-L
1018-8665
Publication state
Published
Issued date
2014
Peer-reviewed
Oui
Volume
228
Number
3
Pages
225-232
Language
english
Notes
Publication types: Journal Article Publication Status: ppublish PDF : Original Paper
Abstract
Background: Fusarium onychomycoses are weakly responsive or unresponsive to standard onychomycosis treatments with oral terbinafine and itraconazole. Objective: To examine whether the use of terbinafine and itraconazole, which are highly effective in fighting Trichophyton onychomycoses, could be a cause of the high incidence of Fusarium nail infections. Methods: Polymerase chain reaction methods were used to detect both Fusarium spp. and Trichophyton spp. in nails of patients who had either received treatment previously or not. Results: No significant microbiological differences were found between treated and untreated patients. In 24 of 79 cases (30%), Fusarium spp. was detected in samples of patients having had no previous antifungal therapy and when Trichophyton spp. grew in culture. Conclusion: Oral terbinafine and itraconazole treatments do not appear to favor the establishment of Fusarium spp. in onychomycosis. © 2014 S. Karger AG, Basel.
Pubmed
Web of science
Create date
04/07/2014 16:55
Last modification date
20/08/2019 14:17
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