OS 03-06 EFFECT OF LONG-TERM ENRICHED POTASSIUM SALT CONSUMPTION ON ALL CAUSES MORTALITY IN CHINESE LIVING IN NURSING HOUSES-A PRELIMINARY ANALYSIS.

Details

Serval ID
serval:BIB_6087399FFA08
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
OS 03-06 EFFECT OF LONG-TERM ENRICHED POTASSIUM SALT CONSUMPTION ON ALL CAUSES MORTALITY IN CHINESE LIVING IN NURSING HOUSES-A PRELIMINARY ANALYSIS.
Journal
Journal of Hypertension
Author(s)
Zhang H., Wang Q., Guo Y., Li D., Zhang B., Dong Y., Huang X., Liu Y., Zhao J., Li W., Brunner H.R., Liu L.
ISSN
1473-5598 (Electronic)
ISSN-L
0263-6352
Publication state
Published
Issued date
2016
Peer-reviewed
Oui
Volume
34 Suppl 1 - ISH 2016 Abstract Book
Pages
e52-e53
Language
english
Notes
Publication types: ARTICLE
Publication Status: ppublish
Abstract
OBJECTIVE: To observe the long-term (3 years) consumption of enriched potassium salt (KCL/NaCL = 1:1 by weight) on all causes mortality and target organ damage in Chinese living in nursing houses.
DESIGN AND METHOD: The study was designed as a single blind prospective intervention. Participants were living in 22 nursing houses in northern China. The nursing houses were randomized into 2 groups: normal salt (control group) and enriched potassium salt (intervention group). The study salt was calculated and dispensed to each nursing house every 3 months. The six-time follow-up visits were carried out during 3 years. Items of the follow-up included questionnaire, physical examination, blood sample and spot urine collection. Data of people moving in or out and of death were collected. The mortality was calculated by observed person-year (p-y).
RESULTS: Totally 1839 people (intervention group 1032, control 807) were analyzed. The baselines of age, SBP, DBP, and urinary sodium to potassium ratio (UNa/K) were not different between control and intervention groups. After using study salt for 3 years, the mean age, blood pressure and UNa/K are listed below. The proportion of impaired kidney function (ratio of microalbumin to creatinine> = 30 mg/g) was 26.8% and 16.2% for control and intervention group respectively (Chi square = 21.683, P < 0.001). The all causes mortality was 82.73/1000 p-y and 48.90/1000 p-y for control and intervention group respectively (Chi square = 28.626, p = 0.000).
CONCLUSIONS: The results demonstrate a beneficial effect of long term enriched K salt consumption on all causes mortality. This might be due to its effect on the blood pressure lowering and/or the beneficial effect on kidney function induced by potassium substitution. Further implementation study of enriched K salt in general population is expected.
Pubmed
Create date
25/10/2016 17:01
Last modification date
21/08/2019 5:16
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