Induction de l'interruption de grossesse au cours du 2e trimestre et evacuation de mort in utero par injections intramusculaires de 15-methyl-PGF2 alpha. [Induction for termination of pregnancy in the second trimester and for delivery of babies dead in utero using intramuscular injections of 15-methyl-PGF2 alpha (author's transl)]

Details

Serval ID
serval:BIB_605699A8E2F1
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Induction de l'interruption de grossesse au cours du 2e trimestre et evacuation de mort in utero par injections intramusculaires de 15-methyl-PGF2 alpha. [Induction for termination of pregnancy in the second trimester and for delivery of babies dead in utero using intramuscular injections of 15-methyl-PGF2 alpha (author's transl)]
Journal
Journal de Gynécologie, Obstétrique et Biologie de la Reproduction
Author(s)
Kunz  B., De Grandi  P.
ISSN
0368-2315 (Print)
Publication state
Published
Issued date
1981
Volume
10
Number
4
Pages
375-84
Notes
English Abstract
Journal Article
Abstract
Intramuscular injection of 15-methyl-PGF2 alpha was used to induce 48 terminations of pregnancy in the second trimester as well as to deliver 8 cases of death in utero and one hydatidiform mole. It is an effective method of treatment with a failure rate of 1.9%. As compared to the administration of pain-relieving drugs intravenously, continuous epidural analgesia has shown itself to be the only method which will allow the best possible conditions for the maintenance and control of prostaglandin induction to be carried out, suppressing effectively even the pains which are associated with uterine contractions brought on by prostaglandin. Although this method of systemic administration of prostaglandin does avoid any intervention through the cervicovaginal route, it does not completely do away with rare infections which are found to complicate matters when PGF2 alpha gel is administered by the extra-amniotic route. All the same, the acceptability and use of this method as a routine method must be limited by the high incidence of episodes of diarrhoea which are made worse by paralysis of the sphincters that is inseparable from epidural analgesia.
Keywords
*Abortifacient Agents *Abortifacient Agents, Nonsteroidal Adolescent Adult Anesthesia, Epidural Carboprost/administration & dosage/*pharmacology Delivery, Obstetric Female Fetal Death Humans Injections, Intramuscular Pregnancy Pregnancy Trimester, Second Prostaglandins F, Synthetic/*pharmacology Uterine Contraction/drug effects (PGF2alpha) were used to induce 48 terminations of pregnancy in the 2nd trimester as well as to deliver 8 cases of fetal death in utero and 1 hydatidiform mole. It is an effective method of treatment with a failure rate of 1.9%. As compared to the administration of pain-relieving drugs intravenously, continuous epidural analgesia has shown itself to be the only method which will allow the best possible conditions for the maintenance and control of PG induction to be carried out, suppressing effectively even the pains which are associated with uterine contractions brought on by PGs. Although the method of systemic administration of PGs does avoid any intervention through the cervicovaginal route, it does not completely do away with rare infections which are found to complicate matters when PGF2alpha gel is administered by the extraamniotic route. Nevertheless, the acceptability and use of this method as a routine method must be limited by the high incidence of episodes of diarrhea which are made worse by the paralysis of sphincters which is inseparable from epidural analgesia. (author's)
Pubmed
Web of science
Create date
25/01/2008 15:39
Last modification date
20/08/2019 14:17
Usage data