Alteration of Bumblebee Venom Composition toward Higher Elevation.

Details

Serval ID
serval:BIB_5E48C9338011
Type
Article: article from journal or magazin.
Collection
Publications
Title
Alteration of Bumblebee Venom Composition toward Higher Elevation.
Journal
Toxins
Author(s)
Barkan N.P., Chevalier M., Pradervand J.N., Guisan A.
ISSN
2072-6651 (Electronic)
ISSN-L
2072-6651
Publication state
Published
Issued date
19/12/2019
Peer-reviewed
Oui
Volume
12
Number
1
Language
english
Notes
Publication types: Journal Article
Publication Status: epublish
Abstract
Venomous animals use venom, a complex biofluid composed of unique mixtures of proteins and peptides, for either predation or defense. Bumblebees, which occur in various habitats due to their unique thermoregulatory properties, mainly use venom for defense. Herein, we conducted an exploratory analysis of the venom composition of a bumblebee species (Bombus pascuorum) along an elevation gradient in the western Swiss Alps using shot-gun proteomic approaches to assess whether their defense mechanism varies along the gradient. The gradient was characterized by high temperatures and low humidity at low elevations and low temperatures and high humidity at high elevations. Venom composition is changing along the elevation gradient, with proteomic variation in the abundances of pain-inducing and allergenic proteins. In particular, the abundance of phospholipase A <sub>2</sub> -like, the main component of bumblebee venom, gradually decreases toward higher elevation (lower temperature), suggesting venom alteration and thus a decrease in bumblebee defense towards harsher environments. Larger datasets may complement this study to validate the observed novel trends.
Keywords
venom, bumblebee, elevation, shot-gun proteomics, mixed-effect model, PLA2-like
Pubmed
Open Access
Yes
Create date
17/12/2019 11:20
Last modification date
04/01/2020 7:17
Usage data