Autologous stem cell transplantation for enteropathy-associated T-cell lymphoma: a retrospective study by the EBMT.

Details

Serval ID
serval:BIB_5E31A5BEE4AD
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Autologous stem cell transplantation for enteropathy-associated T-cell lymphoma: a retrospective study by the EBMT.
Journal
Blood
Author(s)
Jantunen E., Boumendil A., Finel H., Luan J.J., Johnson P., Rambaldi A., Haynes A., Duchosal M.A., Bethge W., Biron P., Carlson K., Craddock C., Rudin C., Finke J., Salles G., Kroschinsky F., Sureda A., Dreger P.
Working group(s)
on behalf of the Lymphoma Working Party of the EBMT
ISSN
1528-0020 (Electronic)
ISSN-L
0006-4971
Publication state
Published
Issued date
2013
Volume
121
Number
13
Pages
2529-2532
Language
english
Notes
Publication types: JOURNAL ARTICLE Publication Status: ppublish. PDF type: Brief Report
Abstract
Enteropathy-associated T-cell lymphoma (EATL) is a rare subtype of peripheral T-cell lymphomas with a poor prognosis. Autologous stem cell transplantation (ASCT) was retrospectively evaluated as a consolidation or salvage strategy for EATL. The analysis included 44 patients who received ASCT for EATL between 2000 and 2010. Thirty-one patients (70%) were in first complete or partial remission at the time of the ASCT. With a median follow-up of 46 months, relapse incidence, progression-free survival, and overall survival were 39%, 54%, and 59% at 4 years, respectively, with only one relapse occurring beyond 18 months posttransplant. There was a trend for better survival in patients transplanted in first complete or partial remission at 4 years (66% vs 36%; P = .062). ASCT is feasible in selected patients with EATL and can yield durable disease control in a significant proportion of the patients.
Pubmed
Web of science
Open Access
Yes
Create date
20/03/2013 14:59
Last modification date
20/08/2019 14:16
Usage data