Radio-frequency tissue ablation of the liver: in vivo and ex vivo experiments with four different systems.

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Serval ID
serval:BIB_5CFE3FC225ED
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Radio-frequency tissue ablation of the liver: in vivo and ex vivo experiments with four different systems.
Journal
European Radiology
Author(s)
Denys A.L., De Baere T., Kuoch V., Dupas B., Chevallier P., Madoff D.C., Schnyder P., Doenz F.
ISSN
0938-7994
Publication state
Published
Issued date
10/2003
Peer-reviewed
Oui
Volume
13
Number
10
Pages
2346-2352
Language
english
Notes
Publication types: Comparative Study ; Journal Article
Abstract
The aim of this study was to test the efficacy of four different radio-frequency ablation (RFA) systems in normal hepatic parenchyma in large animals. The RFA was applied to pig livers in vivo and to calf livers ex vivo using the Radionics cluster needle, RITA starburst XL needle, Radiotherapeutics Le Veen 4.0 needle, and the Berchtold 14-G saline-perfused 15-mm active-tip needle based on constructor specifications. The volume of tissue coagulation from RF was calculated from measurements of the vertical diameter (Dv) and transverse diameter (Dt). Lesion shape was characterized using the ratio between Dt/Dv. Radiotherapeutics and RITA produced in vivo lesion volume of 42+/-10, 39+/-4 cm3 with a reproducible spherical shape (Dt/Dv of 1.01+/-0.16 and 0.97+/-0.1, respectively). Radionics produced in vivo RF lesions volume of 29+/-11 cm3) with an ovoid shape (Dt/Dv 0.88+/-0.09). The RF lesions with the Berchtold device could not be assessed in vivo as 5 of 8 animals died during treatment. Ex vivo RF lesions had similar volumes with each system; however, the Radiotherapeutics device produced more reproducible shaped lesions than the other systems. In our experimental study, we found no difference between expandable needle systems in vivo. Cooled needles produced slightly smaller and ovoid shape in vivo lesions.
Keywords
Animals, Catheter Ablation/adverse effects, Catheter Ablation/instrumentation, Culture Techniques, Electrodes, Equipment Design, Equipment Safety, Female, Liver/injuries, Liver/surgery, Male, Models, Animal, Risk Assessment, Sensitivity and Specificity, Sus scrofa
Pubmed
Web of science
Open Access
Yes
Create date
11/04/2008 12:51
Last modification date
01/10/2019 7:18
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