No benefit of longer eradication therapy of Pseudomonas aeruginosa primoinfections in pediatric cystic fibrosis

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Serval ID
serval:BIB_5B211A93FC66
Type
PhD thesis: a PhD thesis.
Collection
Publications
Institution
Title
No benefit of longer eradication therapy of Pseudomonas aeruginosa primoinfections in pediatric cystic fibrosis
Author(s)
CLAUDE Fabien
Director(s)
HAFEN Gaudenz
Codirector(s)
AUBERT John-David
Institution details
Université de Lausanne, Faculté de biologie et médecine
Publication state
Accepted
Issued date
2019
Language
english
Abstract
Abstract
Objective: Patients with cystic fibrosis are more susceptible than members of the general population to lung infections.
Infections with Pseudomonas aeruginosa require particular attention, because they may accelerate the deterioration of lung function if not adequately treated. This study assessed the eradication rate of P. aeruginosa primoinfections, with a protocol of inhaled tobramycin and oral ciprofloxacin over a 3 months’ period.
Results: Retrospective single-center study from June 1st, 2007 to December 31st, 2015. Inclusion of 28 pediatric patients (11 females, 17 males), with a total of 49 primoinfections. Overall success rate of 67.3%, which is similar or even inferior to figures published in the literature.
Create date
23/08/2019 13:31
Last modification date
24/09/2019 11:47
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