This article examines the relationship between couples’ work–family arrangement and individuals’ perceived work–family conflict (WFC), considering individuals’ attitudes towards gender roles and national gender culture in 37 countries (N = 15,114). Previous research has shown that WFC depends on work and family demands and has mostly accounted for absolute time spent in paid and domestic work. We hypothesize that WFC depends on couples’ work–family arrangement in terms of time spent in paid, domestic and care work. We further expect that the relationship between couples’ work–family arrangement and WFC depends on individuals’ gender attitudes and national gender culture. To test these assumptions, we use the ISSP-2012 data and apply multilevel linear regression analyses. The findings indicate that an egalitarian work–family arrangement—that is, sharing paid, domestic and care work equally with one’s partner—is associated with lower levels of WFC. Moreover, individuals with egalitarian gender attitudes and an egalitarian work–family arrangement experience less WFC than individuals with inconsistent attitudes and behaviours. Individuals with consistent traditional attitudes and behaviours experience the most conflict. Finally, a more egalitarian gender culture relates to less WFC. Cross-level interactions indicate that the relationship between work–family arrangement and WFC is not mediated by countries’ gender culture.