DVT Management and Outcome Trends, 2001 to 2014.

Details

Ressource 1Request a copy Sous embargo indéterminé.
State: Public
Version: author
License: Not specified
Serval ID
serval:BIB_5AD28A85934A
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
DVT Management and Outcome Trends, 2001 to 2014.
Journal
Chest
Author(s)
Morillo R., Jiménez D., Aibar M.Á., Mastroiacovo D., Wells P.S., Sampériz Á., Saraiva de Sousa M., Muriel A., Yusen R.D., Monreal M.
Working group(s)
RIETE investigators
Contributor(s)
Monreal M., Decousus H., Prandoni P., Brenner B., Barba R., Di Micco P., Bertoletti L., Schellong S., Tzoran I., Reis A., Bosevski M., Bounameaux H., Malý R., Wells P., Papadakis M., Agudo P., Aibar M.A., Akasbi M., Alcalde-Manero M., Andújar V., Arcelus J.I., Ballaz A., Barba R., Barrón M., Barrón-Andrés B., Bascuñana J., Blanco-Molina A., Cañas I., Casado I., de Miguel J., Del Toro J., Díaz S., Díaz-Peromingo J.A., Falgá C., Fernández-Capitán C., Font C., Font L., Gallego P., García-Bragado F., García-Rodenas M., Gómez V., González C.J., Grau E., Guirado L., Gutiérrez J., Hernández G., Hernández-Blasco L., Isern V., Jara-Palomares L., Jaras M.J., Jiménez D., Lobo J.L., López-Jiménez L., López-Reyes R., López-Sáez J.B., Lorente M.A., Lorenzo A., Madridano O., Maestre A., Marchena P.J., Martín M., Martín-Antorán J.M., Martín-Martos F., Monreal M., Morales M.V., Nauffal D., Nieto J.A., Nieto S., Núñez M.J., Orbegoso C., Otalora S., Otero R., Pagán B., Pedrajas J.M., Pérez C., Pérez G., Peris M.L., Pons I., Porras J.A., Reig O., Riera-Mestre A., Rivas A., Rodríguez C., Rodríguez-Dávila M.A., Rosa V., Rosa-Murillo A.S., Ruiz-Giménez N., Sahuquillo J.C., Sala M.C., Sampériz A., Sánchez R., Sanz O., Soler S., Suriñach J.M., Tolosa C., Trujillo-Santos J., Uresandi F., Valero B., Valle R., Vela J., Vidal G., Vilar C., Villalta J., Xifre B., Vanassche T., Verhamme P., Wells P., Hirmerova J., Malý R., Tomko T., Celis G., Salgado E., Sánchez G.T., Bertoletti L., Bura-Riviere A., Farge-Bancel D., Hij A., Mahé I., Merah A., Quere I., Papadakis M., Braester A., Brenner B., Tzoran I., Apollonio A., Barillari G., Bertone A., Bilora F., Bucherini E., Ciammaichella M., De Ciantis P., Dentali F., Di Micco P., Duce R., Ferrazzi P., Grandone E., Lessiani G., Lodigiani C., Mastroiacovo D., Pace F., Pesavento R., Pinelli M., Poggio R., Prandoni P., Rosa M., Rota L., Tiraferri E., Tonello D., Tufano A., Venturelli U., Visonà A., Zalunardo B., Drucka E., Kigitovica D., Skride A., Mafalda A., Ribeiro J.L., Sousa M.S., Bosevski M., Zdraveska M., Bounameaux H., Mazzolai L.
ISSN
1931-3543 (Electronic)
ISSN-L
0012-3692
Publication state
Published
Issued date
08/2016
Peer-reviewed
Oui
Volume
150
Number
2
Pages
374-383
Language
english
Notes
Publication types: Journal Article ; Observational Study
Publication Status: ppublish
Abstract
A comprehensive evaluation of temporal trends in the treatment of patients who have DVT may assist with identification of modifiable factors that contribute to short-term outcomes.
We assessed temporal trends in length of hospital stay and use of pharmacological and interventional therapies among 26,695 adults with DVT enrolled in the Registro Informatizado de la Enfermedad TromboEmbólica registry between 2001 and 2014. We also examined temporal trends in risk-adjusted rates of all-cause, pulmonary embolism-related, and bleeding-related death to 30 days after diagnosis.
The mean length of hospital stay decreased from 9.0 days in 2001 to 2005 to 7.6 days in 2010 to 2014 (P < .01). For initial DVT treatment, the use of low-molecular-weight heparin decreased from 98% to 90% (P < .01). Direct oral anticoagulants use increased from 0.5% in 2010 to 13.4% in 2014 (P < .001). Risk-adjusted rates of 30-day all-cause mortality decreased from 3.9% in 2001 to 2005 to 2.7% in 2010 to 2014 (adjusted rate ratio per year, 0.84; 95% CI, 0.74-0.96; P < .01). VTE-related mortality showed a nonstatistically significant downward trend (adjusted rate ratio per year, 0.70; 95% CI, 0.44-1.10; P = .13), whereas 30-day bleeding-related mortality significantly decreased from 0.5% in 2001 to 2005 to 0.1% in 2010-2014 (adjusted rate ratio per year, 0.55; 95% CI, 0.40-0.77; P < .01).
This international registry-based temporal analysis identified reductions in length of stay for adults hospitalized for DVT. The study also found a decreasing trend in adjusted rates of all-cause and bleeding-related mortality.
Keywords
Adult, Aged, Aged, 80 and over, Anticoagulants/therapeutic use, Cause of Death, Cohort Studies, Disease Management, Female, Hemorrhage/chemically induced, Heparin, Low-Molecular-Weight/therapeutic use, Humans, Length of Stay/trends, Male, Middle Aged, Mortality/trends, Population Growth, Prognosis, Registries, Retrospective Studies, Thrombolytic Therapy/statistics & numerical data, Thrombolytic Therapy/trends, Vena Cava Filters/statistics & numerical data, Vena Cava Filters/trends, Venous Thrombosis/mortality, Venous Thrombosis/therapy, DVT, prognosis, survival
Pubmed
Web of science
Create date
26/11/2020 12:00
Last modification date
18/02/2021 7:29
Usage data