Instrumental evaluation of gait modifications before and during intrathecal baclofen therapy: a 2-year follow-up case study.

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State: Public
Version: Final published version
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Serval ID
serval:BIB_5AA49E0EE325
Type
Article: article from journal or magazin.
Collection
Publications
Title
Instrumental evaluation of gait modifications before and during intrathecal baclofen therapy: a 2-year follow-up case study.
Journal
American Journal of Physical Medicine and Rehabilitation / Association of Academic Physiatrists
Author(s)
Molteni F., Carda S., Cazzaniga M., Magoni L., Rossini M., Caimmi M.
ISSN
0894-9115 (Print)
ISSN-L
0894-9115
Publication state
Published
Issued date
2005
Peer-reviewed
Oui
Volume
84
Number
4
Pages
303-306
Language
english
Notes
Publication types: Case Reports ; Journal Article Publication Status: ppublish
Abstract
Intrathecal baclofen therapy has been used for several years, despite the fact that long-term gait modifications in ambulatory patients have not been thoroughly investigated. A 31-yr-old male patient affected by hereditary spastic paraparesis was evaluated clinically and by gait analysis. Evaluations were made before and at 6, 12, 16, and 24 mos after implantation. The patient showed a clear improvement in self-selected speed, step and stride length, knee and ankle kinematics, and ankle kinetics. Moreover, the response observed on self-selected speed is consistent with the intrathecal baclofen dose administered. To our knowledge, this is the first report of a long-term instrumental gait analysis assessment of a patient receiving intrathecal baclofen. Gait analysis could be a reliable and feasible assessment tool to evaluate ambulatory patients receiving intrathecal baclofen therapy over time and to help clinicians in determining exact dose requirements.
Keywords
Adult, Baclofen/therapeutic use, Follow-Up Studies, Gait Disorders, Neurologic/drug therapy, Humans, Injections, Spinal, Male, Muscle Relaxants, Central/therapeutic use, Paraparesis, Spastic/drug therapy, Treatment Outcome
Pubmed
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25/03/2013 18:23
Last modification date
15/07/2020 6:26
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