Candida arteritis in patients who have not received organ transplants: case report and review of the literature.

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Serval ID
serval:BIB_59B8F052AF29
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Candida arteritis in patients who have not received organ transplants: case report and review of the literature.
Journal
Clinical Infectious Diseases
Author(s)
Chapuis-Taillard C., Manuel O., Bille J., Calandra T., Rotman S., Tarr P.E.
ISSN
1537-6591[electronic]
Publication state
Published
Issued date
2008
Volume
46
Number
10
Pages
e106-e111
Language
english
Notes
Publication types: Case Reports ; Journal Article ; Review
Abstract
Fungal arteritis is a rare entity, associated with significant morbidity and mortality, that typically involves graft arteries in solid organ transplant recipients. Here, we report the first case of Candida carotid arteritis and review 22 other cases of Candida arteritis reported since 1966 in patients who have not received transplants. Most patients had serious underlying conditions. All cases were anatomically characterized by pseudoaneurysm formation. Patients presented with fever (n=7), local pain (n=13), and an expanding pulsatile mass (n=4), with subsequent rupture and hemorrhage (n=7). Evidence of Candida colonization or infection was present in 15 patients before arteritis occurred. Treatment typically included a combined surgical and antifungal approach. The outcome was favorable in 11 patients, but follow-up was limited. A high index of suspicion, early diagnosis, and prompt antifungal and surgical treatment seem crucial to efforts to avoid life-threatening arterial rupture and hemorrhage.
Keywords
Adult, Aged, Aged, 80 and over, Aneurysm, False, Aneurysm, Ruptured, Antifungal Agents, Arteritis, Candida, Candidiasis, Female, Humans, Male, Middle Aged, Treatment Outcome
Pubmed
Web of science
Open Access
Yes
Create date
22/05/2008 13:07
Last modification date
25/09/2019 7:09
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