Foodborne botulism, a forgotten yet life-threatening disease: a case report

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Serval ID
serval:BIB_589C977DCA77
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Institution
Title
Foodborne botulism, a forgotten yet life-threatening disease: a case report
Journal
European Review for Medical and Pharmacological Sciences
Author(s)
Feilchenfeldt-Maharoof S., Schaller M-D, Berger M.M., Tsouni P., Kuntzer T., Ben-Hamouda N.
Publication state
Published
Issued date
14/07/2022
Peer-reviewed
Oui
Volume
26
Pages
4770-4773
Language
english
Abstract
OBJECTIVE: Botulism is a very rare disease in Switzerland, with less than one case per year, an incidence of 0.01 cases for 100,000 inhabitants. Indeed, over the past ten years, 9 cases have been reported to Public Health registry. Foodborne botulism (FB) is caused by ingestion of preformed botulinum neurotoxin. Characteristic features should be rapidly recognized, and prompt treatment should be administered to avoid further progression towards respiratory failure and death.
CASE REPORT: We report the case of a patient who developed gastrointestinal symptoms just after a sandwich consumption followed by rapidly progressive cranial nerve impairment, truncal muscle weakness in a descending pattern and respiratory failure requiring mechanical ventilation. The diagnosis of foodborne botulism was delayed due to differential diagnosis considerations. Specific antitoxin therapy was administered immediately after firm clinical conviction of botulism, without waiting for serologic results that later confirmed the diagnosis. As expected, muscle weakness recovery was slow, with persistent chronic deficits nine years later.
CONCLUSIONS: This case highlights differential diagnosis issues of botulism. These include acute neuromuscular disorders such as myasthenia gravis, Guillain-Barré syndrome, or tick-borne encephalitis. The importance of careful medical history and repeated clinical evaluation to avoid misdiagnosis can be lifesaving. Our case highlights the typical warning signs.
Pubmed
Open Access
Yes
Create date
20/04/2022 16:31
Last modification date
30/08/2022 5:41
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