Prenatal ultrasonographic detection of gastrointestinal obstruction: results from 18 European congenital anomaly registries.

Details

Serval ID
serval:BIB_5789C7D60FE4
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Prenatal ultrasonographic detection of gastrointestinal obstruction: results from 18 European congenital anomaly registries.
Journal
Prenatal Diagnosis
Author(s)
Haeusler M.C., Berghold A., Stoll C., Barisic I., Clementi M.
Working group(s)
EUROSCAN study group
ISSN
0197-3851
Publication state
Published
Issued date
2002
Peer-reviewed
Oui
Volume
22
Number
7
Pages
616-623
Language
english
Notes
(Addor M.C. included in the EUROSCAN study group)
Abstract
OBJECTIVES: We evaluated the prenatal detection of gastrointestinal obstruction (GIO, including atresia, stenosis, absence or fistula) by routine ultrasonographic examination in an unselected population all over Europe. METHODS: Data from 18 congenital malformation registries in 11 European countries were analysed. These multisource registries used the same methodology. All fetuses/neonates with GIO confirmed within 1 week after birth who had prenatal sonography and were born during the study period (1 July 1996 to 31 December 1998) were included. RESULTS: There were 670 793 births in the area covered and 349 fetuses/neonates had GIO. The prenatal detection rate of GIO was 34%; of these 40% were detected < or = 24 weeks of gestation (WG). A total of 31% (60/192) of the isolated GIO were detected prenatally, as were 38% (59/157) of the associated GIO (p=0.26). The detection rate was 25% for esophageal obstruction (31/122), 52% for duodenal obstruction (33/64), 40% for small intestine obstruction (27/68) and 29% for large intestine obstruction (28/95) (p=0.002). The detection rate was higher in countries with a policy of routine obstetric ultrasound. Fifteen percent of pregnancies were terminated (51/349). Eleven of these had chromosomal anomalies, 31 multiple malformations, eight non-chromosomal recognized syndromes, and one isolated GIO. The participating registries reflect the various national policies for termination of pregnancy (TOP), but TOPs after 24 WG (11/51) do not appear to be performed more frequently in countries with a liberal TOP policy. CONCLUSION: This European study shows that the detection rate of GIO depends on the screening policy and on the sonographic detectability of GIO subgroups.
Keywords
Adult, Congenital Abnormalities, Diagnostic Tests, Routine, Digestive System Abnormalities, Europe, Female, Humans, Infant, Newborn, Intestinal Obstruction, Male, Mass Screening, Pregnancy, Registries, Sex Factors, Ultrasonography, Prenatal
Pubmed
Web of science
Create date
31/03/2009 11:29
Last modification date
20/08/2019 14:11
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