Assessing the Impact of Prolonged Averaging of Coronary Continuous Thermodilution Traces.

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Version: Final published version
License: CC BY 4.0
Serval ID
serval:BIB_57825CF8B15C
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Assessing the Impact of Prolonged Averaging of Coronary Continuous Thermodilution Traces.
Journal
Diagnostics
Author(s)
Fawaz S., Munhoz D., Mahendiran T., Gallinoro E., Mizukami T., Khan S.A., Simpson RFG, Svanerud J., Cook C.M., Davies J.R., Karamasis G.V., De Bruyne B., Keeble T.R.
ISSN
2075-4418 (Print)
ISSN-L
2075-4418
Publication state
Published
Issued date
28/01/2024
Peer-reviewed
Oui
Volume
14
Number
3
Language
english
Notes
Publication types: Journal Article
Publication Status: epublish
Abstract
Continuous Thermodilution is a novel method of quantifying coronary flow (Q) in mL/min. To account for variability of Q within the cardiac cycle, the trace is smoothened with a 2 s moving average filter. This can sometimes be ineffective due to significant heart rate variability, ventricular extrasystoles, and deep inspiration, resulting in a fluctuating temperature trace and ambiguity in the location of the "steady state". This study aims to assess whether a longer moving average filter would smoothen any fluctuations within the continuous thermodilution traces resulting in improved interpretability and reproducibility on a test-retest basis. Patients with ANOCA underwent repeat continuous thermodilution measurements. Analysis of traces were performed at averages of 10, 15, and 20 s to determine the maximum acceptable average. The maximum acceptable average was subsequently applied as a moving average filter and the traces were re-analysed to assess the practical consequences of a longer moving average. Reproducibility was then assessed and compared to a 2 s moving average. Of the averages tested, only 10 s met the criteria for acceptance. When the data was reanalysed with a 10 s moving average filter, there was no significant improvement in reproducibility, however, it resulted in a 12% diagnostic mismatch. Applying a longer moving average filter to continuous thermodilution data does not improve reproducibility. Furthermore, it results in a loss of fidelity on the traces, and a 12% diagnostic mismatch. Overall, current practice should be maintained.
Keywords
Cmd, Coroflow, continuous thermodilution, coronary, microvascular, CMD
Pubmed
Web of science
Open Access
Yes
Create date
15/02/2024 16:20
Last modification date
09/08/2024 14:59
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