Assessing the Impact of Prolonged Averaging of Coronary Continuous Thermodilution Traces.
Details
Serval ID
serval:BIB_57825CF8B15C
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Assessing the Impact of Prolonged Averaging of Coronary Continuous Thermodilution Traces.
Journal
Diagnostics
ISSN
2075-4418 (Print)
ISSN-L
2075-4418
Publication state
Published
Issued date
28/01/2024
Peer-reviewed
Oui
Volume
14
Number
3
Language
english
Notes
Publication types: Journal Article
Publication Status: epublish
Publication Status: epublish
Abstract
Continuous Thermodilution is a novel method of quantifying coronary flow (Q) in mL/min. To account for variability of Q within the cardiac cycle, the trace is smoothened with a 2 s moving average filter. This can sometimes be ineffective due to significant heart rate variability, ventricular extrasystoles, and deep inspiration, resulting in a fluctuating temperature trace and ambiguity in the location of the "steady state". This study aims to assess whether a longer moving average filter would smoothen any fluctuations within the continuous thermodilution traces resulting in improved interpretability and reproducibility on a test-retest basis. Patients with ANOCA underwent repeat continuous thermodilution measurements. Analysis of traces were performed at averages of 10, 15, and 20 s to determine the maximum acceptable average. The maximum acceptable average was subsequently applied as a moving average filter and the traces were re-analysed to assess the practical consequences of a longer moving average. Reproducibility was then assessed and compared to a 2 s moving average. Of the averages tested, only 10 s met the criteria for acceptance. When the data was reanalysed with a 10 s moving average filter, there was no significant improvement in reproducibility, however, it resulted in a 12% diagnostic mismatch. Applying a longer moving average filter to continuous thermodilution data does not improve reproducibility. Furthermore, it results in a loss of fidelity on the traces, and a 12% diagnostic mismatch. Overall, current practice should be maintained.
Keywords
Cmd, Coroflow, continuous thermodilution, coronary, microvascular, CMD
Pubmed
Web of science
Open Access
Yes
Create date
15/02/2024 16:20
Last modification date
09/08/2024 14:59