Nouvelles thérapies en rhumatologie pédiatrique [New therapies in pediatric rheumatology]

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State: Public
Version: Final published version
License: CC BY-NC-ND 4.0
Serval ID
serval:BIB_55E48DB2D309
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Nouvelles thérapies en rhumatologie pédiatrique [New therapies in pediatric rheumatology]
Journal
Revue medicale suisse
Author(s)
Bellutti Enders F., Von Scheven-Gête A., Vanoni F., Fonjallaz B., Hofer M.
ISSN
1660-9379 (Print)
ISSN-L
1660-9379
Publication state
Published
Issued date
22/02/2012
Peer-reviewed
Oui
Volume
8
Number
329
Pages
418-422
Language
french
Notes
Publication types: English Abstract ; Journal Article
Publication Status: ppublish
Abstract
Biotherapies are recent treatments, which target molecules implicated in the pathogenesis of inflammatory diseases. In pediatric rheumatology, we use anti-TNF-alpha and abatacept in JIA patients with polyarticular involvement, whereas anti-IL-6 and anti-IL-1 blockers are efficacious in the systemic form of JIA and other auto-inflammatory conditions. These new treatments have significantly improved the control of articular and systemic inflammation and the prognosis of rheumatic diseases. Their effect and their safety on the long-term need to be assessed on large cohorts of patients. Due to the impact of these chronic illnesses on the young patient and its family, and the required specific knowledge, the care of these children should be provided by a multidisciplinary team linked to a centre of competence.
Keywords
Biological Products/therapeutic use, Child, Humans, Rheumatic Diseases/drug therapy
Pubmed
Create date
06/06/2012 18:05
Last modification date
17/12/2024 7:14
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