The Role of Fluorine-18-fluorodeoxyglucose Positron Emission Tomography in Assessing the Response to Neoadjuvant Treatment in Patients with Osteosarcoma.

Details

Serval ID
serval:BIB_55B5B887B560
Type
Article: article from journal or magazin.
Collection
Publications
Title
The Role of Fluorine-18-fluorodeoxyglucose Positron Emission Tomography in Assessing the Response to Neoadjuvant Treatment in Patients with Osteosarcoma.
Journal
International journal of molecular imaging
Author(s)
Caldarella C., Salsano M., Isgrò M.A., Treglia G.
ISSN
2090-1720 (Electronic)
ISSN-L
2090-1720
Publication state
Published
Issued date
2012
Peer-reviewed
Oui
Volume
2012
Pages
870301
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Abstract
Aim. The objective of this study is to systematically review the role of positron emission tomography (PET) and PET/computed tomography (PET/CT) with fluorine-18-fluorodeoxyglucose (FDG) in assessing the response to neoadjuvant treatment in patients with osteosarcoma (OS). Methods. A comprehensive literature search of published studies through March 2012 in PubMed/MEDLINE, Embase, and Scopus databases regarding whole-body FDG-PET and FDG-PET/CT in patients with OS was performed. Results. Twenty-two studies have investigated the role of FDG-PET and FDG-PET/CT in the evaluation of response to neoadjuvant treatment with either chemotherapy or radiation therapy in patients with OS. The main findings of these studies are presented. Conclusion. FDG-PET or PET/CT seems to be sensitive and reliable diagnostic tools in the assessment of metabolic response to treatment in patients with OS, after baseline PET evaluation has been performed in advance. However, false positive findings due to inflammation in sites of tumoral response should be considered.

Pubmed
Open Access
Yes
Create date
20/08/2017 20:21
Last modification date
20/08/2019 14:10
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