Ultra-rapid high-performance liquid chromatographic screening for phenothiazines in human samples.

Details

Serval ID
serval:BIB_53F7F9423C4A
Type
Article: article from journal or magazin.
Collection
Publications
Title
Ultra-rapid high-performance liquid chromatographic screening for phenothiazines in human samples.
Journal
Analyst
Author(s)
Kintz P., Lamant J.M., Mangin P.
ISSN
0003-2654[print], 0003-2654[linking]
Publication state
Published
Issued date
1990
Volume
115
Number
9
Pages
1269-1270
Language
english
Abstract
A high-performance liquid chromatographic method is presented for the simultaneous identification and quantification of six commonly prescribed phenothiazines. Single-step extraction was achieved from alkaline samples with heptane - isoamyl alcohol (98.5 + 1.5), using prochlorperazine as an internal standard. A Spherisorb CN column was used, with a mobile phase of acetonitrile - acetate buffer (95 + 5). Detection was carried out at 254 nm.
Keywords
Chromatography, High Pressure Liquid/methods, Humans, Phenothiazines/blood
Pubmed
Create date
15/10/2010 16:14
Last modification date
20/08/2019 15:09
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