Suivi thérapeutique des médicaments (II). La pratique clinique [Therapeutic drug monitoring: clinical practice].

Details

Serval ID
serval:BIB_53F56A1C36B3
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Title
Suivi thérapeutique des médicaments (II). La pratique clinique [Therapeutic drug monitoring: clinical practice].
Journal
Revue Médicale Suisse
Author(s)
Widmer N., Werner D., Grouzmann E., Eap C.B., Marchetti O., Fayet A., Csajka C., Decosterd L.A., Buclin T.
ISSN
1660-9379 (Print)
ISSN-L
1660-9379
Publication state
Published
Issued date
2008
Peer-reviewed
Oui
Volume
4
Number
165
Pages
1649-1660
Language
french
Notes
Publication types: English Abstract ; Journal Article
Publication Status: ppublish
Abstract
When requesting a blood level measurement in the context of "Therapeutic drug monitoring" (TDM), numerous aspects have to be considered in the pre-analytical and analytical area, as in the integration of associated clinical data. This review presents therapeutic classes for which a clinical benefit of TDM is established or suggested, at least in some settings. For each class of drugs, the main pharmacokinetic, pre-analytical, analytical and clinical aspects are evaluated in the scope of such a monitoring. Each step of the TDM process is important and none should be neglected. Additional clinical trials are however warranted to better establish the exact conditions of use for such a monitoring.
Keywords
Anti-Bacterial Agents/blood, Anti-Bacterial Agents/pharmacokinetics, Anti-Retroviral Agents/blood, Anti-Retroviral Agents/pharmacokinetics, Anticonvulsants/blood, Anticonvulsants/pharmacokinetics, Antineoplastic Agents/blood, Antineoplastic Agents/pharmacokinetics, Antiparasitic Agents/blood, Antiparasitic Agents/pharmacokinetics, Antitubercular Agents/blood, Antitubercular Agents/pharmacokinetics, Cardiovascular Agents/blood, Cardiovascular Agents/pharmacokinetics, Dose-Response Relationship, Drug, Drug Monitoring/methods, Drug Monitoring/standards, Evidence-Based Medicine, Humans, Immunosuppressive Agents/blood, Immunosuppressive Agents/pharmacokinetics, Product Surveillance, Postmarketing, Psychotropic Drugs/blood, Psychotropic Drugs/pharmacokinetics
Pubmed
Create date
24/02/2009 18:20
Last modification date
20/08/2019 15:08
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