Les micro-ARN - Nouveaux acteurs du contrôle hypothalamique de la fertilité [MicroRNAs: new players in the hypothalamic control of fertility]

Details

Serval ID
serval:BIB_53B7ED3CE3C2
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Les micro-ARN - Nouveaux acteurs du contrôle hypothalamique de la fertilité [MicroRNAs: new players in the hypothalamic control of fertility]
Journal
Medecine sciences
Author(s)
Messina A., Langlet F., Prevot V.
ISSN
1958-5381 (Electronic)
ISSN-L
0767-0974
Publication state
Published
Issued date
05/2017
Peer-reviewed
Oui
Volume
33
Number
5
Pages
506-511
Language
french
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Abstract
MicroRNAs are small non-coding RNAs that modulate gene expression post-transcriptionally. Discovered more than 15 years ago, their functions start to be unraveled. Increasing evidence points to an important functional role of microRNAs in brain development. In particular, miRNAs have recently been established to play a vital role in the mechanisms underlying the infantile rise in gonadotropin-releasing hormone (GnRH) production by neurons in the hypothalamus, a phenomenon necessary for the onset of puberty in mammals.

Keywords
Animals, Fertility/genetics, Fertility/physiology, Humans, Hypothalamus/metabolism, Hypothalamus/physiology, Mammals/genetics, Mammals/growth & development, Mammals/physiology, MicroRNAs/physiology, Neurons/physiology
Pubmed
Web of science
Open Access
Yes
Create date
22/06/2017 17:22
Last modification date
21/10/2020 6:28
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