Causes of blindness and vision impairment in 2020 and trends over 30 years, and prevalence of avoidable blindness in relation to VISION 2020: the Right to Sight: an analysis for the Global Burden of Disease Study.
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Version: Final published version
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Serval ID
serval:BIB_5308088229A9
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Causes of blindness and vision impairment in 2020 and trends over 30 years, and prevalence of avoidable blindness in relation to VISION 2020: the Right to Sight: an analysis for the Global Burden of Disease Study.
Journal
The Lancet. Global health
Working group(s)
GBD 2019 Blindness and Vision Impairment Collaborators, Vision Loss Expert Group of the Global Burden of Disease Study
Contributor(s)
Bourne RRA, Briant P.S., Flaxman S.R., Taylor HRB, Jonas J.B., Abdoli A.A., Abrha W.A., Abualhasan A., Abu-Gharbieh E.G., Adal T.G., Afshin A., Ahmadieh H., Alemayehu W., Alemzadeh SAS, Alfaar A.S., Alipour V., Androudi S., Arabloo J., Arditi A.B., Aregawi B.B., Arrigo A., Ashbaugh C., Ashrafi E.D., Atnafu D.D., Bagli E.A., Baig AAW, Bärnighausen T.W., Battaglia Parodi M., Beheshti M.S., Bhagavathula A.S., Bhardwaj N., Bhardwaj P., Bhattacharyya K., Bijani A., Bikbov M., Bottone M., Braithwaite T.M., Bron A.M., Burugina Nagaraja S.A., Butt Z.A., Caetano Dos Santos FLL, Carneiro VLJ, Casson R.J., Cheng C.J., Choi J.J., Chu D.T., Cicinelli MVM, Coelho JMG, Congdon NGA, Couto RAA, Cromwell EAM, Dahlawi S.M., Dai X., Dana R., Dandona L., Dandona R.A., Del Monte M.A., Derbew Molla M., Dervenis N.A., Desta AAP, Deva J.P., Diaz D., Djalalinia S.E., Ehrlich J.R., Elayedath R.R., Elhabashy HRB, Ellwein L.B., Emamian M.H., Eskandarieh S., Farzadfar F.G., Fernandes A.G., Fischer F.S., Friedman DSM, Furtado J.M., Gaidhane S., Gazzard G., Gebremichael B., George R., Ghashghaee A., Gilani S.A., Golechha M., Hamidi S.R., Hammond BRR, Hartnett MERK, Hartono R.K., Hashi A.I., Hay S.I., Hayat K., Heidari G., Ho H.C., Holla R., Househ M.J., Huang JJE, Ibitoye SEM, Ilic IMD, Ilic MDD, Ingram ADN, Irvani SSN, Islam SMS, Itumalla R., Jayaram S.P., Jha R.P., Kahloun R., Kalhor R., Kandel H., Kasa A.S., Kavetskyy T.A., Kayode GAH, Kempen J.H., Khairallah M., Khalilov R.A., Khan EAC, Khanna R.C., Khatib MNA, Khoja TAE, Kim J.E., Kim Y.J., Kim G.R., Kisa S., Kisa A., Kosen S., Koyanagi A., Kucuk Bicer B., Kulkarni V.P., Kurmi O.P., Landires I.C., Lansingh VCL, Leasher JLE, LeGrand K.E., Leveziel N., Limburg H., Liu X., Madhava Kunjathur S., Maleki S., Manafi N., Mansouri K., McAlinden C.G., Meles GGM, Mersha A.M., Michalek IMR, Miller T.R., Misra S., Mohammad Y., Mohammadi SFA, Mohammed JAH, Mokdad A.H., Moni MAA, Montasir AAR, Morse ARF, Mulaw GFC, Naderi M., Naderifar H.S., Naidoo K.S., Naimzada M.D., Nangia V., Narasimha Swamy S.M., Naveed D.M., Negash H.L., Nguyen H.L., Nunez-Samudio V.A., Ogbo F.A., Ogundimu K.T., Olagunju ATE, Onwujekwe O.E., Otstavnov N.O., Owolabi M.O., Pakshir K., Panda-Jonas S., Parekh U., Park E.C., Pasovic M., Pawar S., Pesudovs K., Peto T.Q., Pham H.Q., Pinheiro M., Podder V., Rahimi-Movaghar V., Rahman MHUY, Ramulu P.Y., Rathi P., Rawaf S.L., Rawaf D.L., Rawal L., Reinig N.M., Renzaho A.M., Rezapour A.L., Robin A.L., Rossetti L., Sabour S., Safi S., Sahebkar A., Sahraian MAM, Samy A.M., Sathian B., Saya G.K., Saylan M.A., Shaheen AAA, Shaikh MAT, Shen T.T., Shibuya K.S., Shiferaw W.S., Shigematsu M., Shin J.I., Silva J.C., Silvester A.A., Singh J.A., Singhal D.S., Sitorus R.S., Skiadaresi E.Y., Skryabin VYA, Skryabina A.A., Soheili A.B., Sorrie MBARC, Sousa RARCT, Sreeramareddy C.T., Stambolian D.G., Tadesse E.G., Tahhan N.I., Tareque M.I., Topouzis F.X., Tran B.X., Tsegaye G.K., Tsilimbaris M.K., Varma R., Virgili G., Vongpradith A.T., Vu G.T., Wang Y.X., Wang N.H., Weldemariam AHK, West SKG, Wondmeneh TGY, Wong T.Y., Yaseri M., Yonemoto N., Yu C.S., Zastrozhin M.S., Zhang Z.R., Zimsen S.R., Resnikoff S., Vos T.
ISSN
2214-109X (Electronic)
ISSN-L
2214-109X
Publication state
Published
Issued date
02/2021
Peer-reviewed
Oui
Volume
9
Number
2
Pages
e144-e160
Language
english
Notes
Publication types: Journal Article ; Meta-Analysis ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S. ; Systematic Review
Publication Status: ppublish
Publication Status: ppublish
Abstract
Many causes of vision impairment can be prevented or treated. With an ageing global population, the demands for eye health services are increasing. We estimated the prevalence and relative contribution of avoidable causes of blindness and vision impairment globally from 1990 to 2020. We aimed to compare the results with the World Health Assembly Global Action Plan (WHA GAP) target of a 25% global reduction from 2010 to 2019 in avoidable vision impairment, defined as cataract and undercorrected refractive error.
We did a systematic review and meta-analysis of population-based surveys of eye disease from January, 1980, to October, 2018. We fitted hierarchical models to estimate prevalence (with 95% uncertainty intervals [UIs]) of moderate and severe vision impairment (MSVI; presenting visual acuity from <6/18 to 3/60) and blindness (<3/60 or less than 10° visual field around central fixation) by cause, age, region, and year. Because of data sparsity at younger ages, our analysis focused on adults aged 50 years and older.
Global crude prevalence of avoidable vision impairment and blindness in adults aged 50 years and older did not change between 2010 and 2019 (percentage change -0·2% [95% UI -1·5 to 1·0]; 2019 prevalence 9·58 cases per 1000 people [95% IU 8·51 to 10·8], 2010 prevalence 96·0 cases per 1000 people [86·0 to 107·0]). Age-standardised prevalence of avoidable blindness decreased by -15·4% [-16·8 to -14·3], while avoidable MSVI showed no change (0·5% [-0·8 to 1·6]). However, the number of cases increased for both avoidable blindness (10·8% [8·9 to 12·4]) and MSVI (31·5% [30·0 to 33·1]). The leading global causes of blindness in those aged 50 years and older in 2020 were cataract (15·2 million cases [9% IU 12·7-18·0]), followed by glaucoma (3·6 million cases [2·8-4·4]), undercorrected refractive error (2·3 million cases [1·8-2·8]), age-related macular degeneration (1·8 million cases [1·3-2·4]), and diabetic retinopathy (0·86 million cases [0·59-1·23]). Leading causes of MSVI were undercorrected refractive error (86·1 million cases [74·2-101·0]) and cataract (78·8 million cases [67·2-91·4]).
Results suggest eye care services contributed to the observed reduction of age-standardised rates of avoidable blindness but not of MSVI, and that the target in an ageing global population was not reached.
Brien Holden Vision Institute, Fondation Théa, The Fred Hollows Foundation, Bill & Melinda Gates Foundation, Lions Clubs International Foundation, Sightsavers International, and University of Heidelberg.
We did a systematic review and meta-analysis of population-based surveys of eye disease from January, 1980, to October, 2018. We fitted hierarchical models to estimate prevalence (with 95% uncertainty intervals [UIs]) of moderate and severe vision impairment (MSVI; presenting visual acuity from <6/18 to 3/60) and blindness (<3/60 or less than 10° visual field around central fixation) by cause, age, region, and year. Because of data sparsity at younger ages, our analysis focused on adults aged 50 years and older.
Global crude prevalence of avoidable vision impairment and blindness in adults aged 50 years and older did not change between 2010 and 2019 (percentage change -0·2% [95% UI -1·5 to 1·0]; 2019 prevalence 9·58 cases per 1000 people [95% IU 8·51 to 10·8], 2010 prevalence 96·0 cases per 1000 people [86·0 to 107·0]). Age-standardised prevalence of avoidable blindness decreased by -15·4% [-16·8 to -14·3], while avoidable MSVI showed no change (0·5% [-0·8 to 1·6]). However, the number of cases increased for both avoidable blindness (10·8% [8·9 to 12·4]) and MSVI (31·5% [30·0 to 33·1]). The leading global causes of blindness in those aged 50 years and older in 2020 were cataract (15·2 million cases [9% IU 12·7-18·0]), followed by glaucoma (3·6 million cases [2·8-4·4]), undercorrected refractive error (2·3 million cases [1·8-2·8]), age-related macular degeneration (1·8 million cases [1·3-2·4]), and diabetic retinopathy (0·86 million cases [0·59-1·23]). Leading causes of MSVI were undercorrected refractive error (86·1 million cases [74·2-101·0]) and cataract (78·8 million cases [67·2-91·4]).
Results suggest eye care services contributed to the observed reduction of age-standardised rates of avoidable blindness but not of MSVI, and that the target in an ageing global population was not reached.
Brien Holden Vision Institute, Fondation Théa, The Fred Hollows Foundation, Bill & Melinda Gates Foundation, Lions Clubs International Foundation, Sightsavers International, and University of Heidelberg.
Keywords
Aged, Aged, 80 and over, Blindness/epidemiology, Blindness/etiology, Blindness/prevention & control, Cataract/complications, Eye Diseases/complications, Female, Glaucoma/complications, Global Burden of Disease/trends, Global Health/trends, Humans, Macular Degeneration/complications, Male, Middle Aged, Refractive Errors/complications, Vision Disorders/epidemiology, Vision Disorders/etiology, Vision Disorders/prevention & control, Vision, Low/epidemiology, Vision, Low/etiology, Vision, Low/prevention & control, Visual Acuity
Pubmed
Web of science
Open Access
Yes
Create date
16/04/2021 19:31
Last modification date
09/08/2024 15:53