Carotid Artery Plaque Progression: Proposal of a New Predictive Score and Role of Carotid Intima-Media Thickness.

Details

Serval ID
serval:BIB_50C3B6676B40
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Carotid Artery Plaque Progression: Proposal of a New Predictive Score and Role of Carotid Intima-Media Thickness.
Journal
International journal of environmental research and public health
Author(s)
Brunelli N., Altamura C., Costa C.M., Altavilla R., Palazzo P., Maggio P., Marcosano M., Vernieri F.
ISSN
1660-4601 (Electronic)
ISSN-L
1660-4601
Publication state
Published
Issued date
11/01/2022
Peer-reviewed
Oui
Volume
19
Number
2
Pages
758
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: epublish
Abstract
We aimed to investigate if the carotid intima-media thickness (IMT) at baseline and the HAD <sub>2</sub> S score, composed of the sum of single risk factors (hypertension, age ≥ 75 years, diabetes, dyslipidemia, smoking), were predictive of plaque progression.
We performed a retrospective analysis on real-life prospectively collected data from patients with any detectable carotid plaque at follow up. The plaque score, calculated at baseline (T0) and at a median follow up of 36.6 months (IQR 39.6-34.3) (T3), was defined as 0: no plaque or stenosis < 30%; 1: stenosis in the range 30-49%; 2: in the range 50-69%; 3: in the range 70-99% and 4: occlusion. Carotid IMT was measured at T0 and T3; HAD <sub>2</sub> S score was calculated at baseline.
We included 340 patients with a mean age of 69.9 (9.1) years and 25.3% subjects had plaque progression. Individuals with progression had a median HAD <sub>2</sub> S score of 3 (1) while those without progression had 2 (1). Patients with progression had a mean baseline IMT of 0.86 (0.17) while those without progression had 0.77 (0.18) (p < 0.0001). A correlation between progression and baseline IMT was found (p = 0.002).
Baseline IMT could be considered a predictor of progression. Patients with progression had an HAD <sub>2</sub> S score higher than those without evolution.
Keywords
Aged, Carotid Artery Diseases, Carotid Intima-Media Thickness, Carotid Stenosis, Humans, Predictive Value of Tests, Retrospective Studies, Risk Factors, HAD2S score, carotid intima-media thickness, carotid plaque progression, cerebrovascular disease
Pubmed
Web of science
Open Access
Yes
Create date
31/01/2022 11:36
Last modification date
18/11/2023 7:07
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