A fatal case of betaxolol poisoning.

Details

Serval ID
serval:BIB_505BDA4B301E
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Title
A fatal case of betaxolol poisoning.
Journal
Journal of Analytical Toxicology
Author(s)
Berthault F., Kintz P., Tracqui A., Mangin P.
ISSN
0146-4760[print], 0146-4760[linking]
Publication state
Published
Issued date
1997
Volume
21
Number
3
Pages
228-231
Language
english
Abstract
We report the first case in the literature of fatal betaxolol (Kerlone) self-poisoning. After a single-step liquid-liquid alkaline extraction, betaxolol was identified by a high-performance liquid chromatographic-diode array detection screening procedure and then quantitated in cardiac blood, heart, brain, muscle, spleen, stomach contents, duodenum contents, liver, and kidney. The blood betaxolol concentration was 36 mg/L.
Keywords
Adrenergic beta-Antagonists/blood, Adrenergic beta-Antagonists/metabolism, Adult, Autopsy, Betaxolol/blood, Betaxolol/metabolism, Brain/metabolism, Chromatography, High Pressure Liquid, Female, Gastrointestinal Contents/chemistry, Humans, Kidney/metabolism, Liver/metabolism, Muscles/metabolism, Myocardium/metabolism, Reference Standards, Spleen/metabolism, Suicide, Tissue Distribution
Pubmed
Create date
19/10/2010 17:16
Last modification date
03/03/2018 17:08
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