Negative 18F-FET PET/CT in brain metastasis recurrence: a teaching case report.

Details

Serval ID
serval:BIB_50442C996C6C
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Negative 18F-FET PET/CT in brain metastasis recurrence: a teaching case report.
Journal
European journal of hybrid imaging
Author(s)
Alshehri S., Prior J., Moshebah M., Schiappacasse L., Dunet V.
ISSN
2510-3636 (Electronic)
ISSN-L
2510-3636
Publication state
Published
Issued date
22/11/2021
Peer-reviewed
Oui
Volume
5
Number
1
Pages
21
Language
english
Notes
Publication types: Journal Article
Publication Status: epublish
Abstract
Positron emission tomography (PET) using O-(2-[ <sup>18</sup> F]fluoroethyl)-L-tyrosine ( <sup>18</sup> F-FET) PET has been shown to be a useful tool for differentiating radiation therapy outcomes, such as brain metastasis recurrence or radiation necrosis. We present the case of a female patient with brain metastases from pulmonary mucinous adenocarcinoma with suspicion of tumor recurrence on follow-up magnetic resonance imaging (MRI) after radiosurgery. <sup>18</sup> F-FET PET/computed tomography (CT) was indicative of radiation necrosis. Due to the patient's medical history and the discrepancy between the brain MRI and PET/CT results, surgical biopsies were decided, which were positive for brain metastasis recurrence. The diagnosis of metastasis recurrence may also be challenging on <sup>18</sup> F-FET PET/CT. In case of discrepancies between MRI and PET/CT results, false-negative <sup>18</sup> F-FET PET/CT remains a possibility and requires careful follow-up or biopsy.
Keywords
Brain, Metastasis, Necrosis, Radiation
Pubmed
Web of science
Open Access
Yes
Create date
03/12/2021 18:58
Last modification date
04/03/2022 7:33
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