Intestinal lymphatic vasculature: structure, mechanisms and functions.

Details

Serval ID
serval:BIB_50281243EFF5
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Intestinal lymphatic vasculature: structure, mechanisms and functions.
Journal
Nature reviews. Gastroenterology & hepatology
Author(s)
Bernier-Latmani J., Petrova T.V.
ISSN
1759-5053 (Electronic)
ISSN-L
1759-5045
Publication state
Published
Issued date
09/2017
Peer-reviewed
Oui
Volume
14
Number
9
Pages
510-526
Language
english
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Abstract
The mammalian intestine is richly supplied with lymphatic vasculature, which has functions ranging from maintenance of interstitial fluid balance to transport of antigens, antigen-presenting cells, dietary lipids and fat-soluble vitamins. In this Review, we provide in-depth information concerning the organization and structure of intestinal lymphatics, the current view of their developmental origins, as well as molecular mechanisms of intestinal lymphatic patterning and maintenance. We will also discuss physiological aspects of intestinal lymph flow regulation and the known and emerging roles of intestinal lymphatic vessels in human diseases, such as IBD, infection and cancer.

Keywords
Humans, Intestinal Mucosa/physiology, Lymphatic Vessels/physiology
Pubmed
Web of science
Create date
06/07/2017 16:37
Last modification date
20/08/2019 14:06
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