Endoscopic and surgical ampullectomy for non-invasive ampullary tumors: Short-term outcomes.

Details

Serval ID
serval:BIB_501F5E3B80C5
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Endoscopic and surgical ampullectomy for non-invasive ampullary tumors: Short-term outcomes.
Journal
Bioscience trends
Author(s)
Dubois M., Labgaa I., Dorta G., Halkic N.
ISSN
1881-7823 (Electronic)
ISSN-L
1881-7815
Publication state
Published
Issued date
16/01/2017
Peer-reviewed
Oui
Volume
10
Number
6
Pages
507-511
Language
english
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Abstract
Non-invasive ampullary tumors, may be treated with endoscopic (EA) or surgical ampullectomy (SA). However, evidence on the morbidity of these techniques remains limited. This pilot study aimed to assess and compare morbidity of EA and SA. Patients undergoing EA or SA for non-invasive ampullary tumors were retrospectively analyzed and compared. Outcomes were postoperative complications graded with Clavien Classification and Comprehensive Complication Index (CCI), and length of stay (LoS). A review of the literature was performed to propose an evidence-based algorithm to treat ampullary tumors. A total of 11 EA and 19 SA were identified and analyzed. EA was associated with shorter intervention (51 vs. 191 min, p < 0.001) and decreased blood loss (0 vs. 100 mL, p < 0.001). Postoperative complications were more frequent after surgery compared to endoscopy (9% vs. 68%, p = 0.002). Surgical patients showed a higher CCI (0 vs. 8.7, p < 0.001). LoS was reduced in patients undergoing endoscopy (0 vs. 14 days, p < 0.001), with comparable readmissions rates (p = 0.126). Necessity of subsequent treatment was more frequent after endoscopic, compared to SA (5 vs. 1, p = 0.016). EA was associated with lower morbidity than SA and appeared as an appropriate first-line treatment for non-invasive ampullary tumors. SA remains a valuable alternative after EA failure.

Keywords
Algorithms, Cell Proliferation/physiology, Duodenal Neoplasms/diagnosis, Duodenal Neoplasms/surgery, Humans
Pubmed
Web of science
Create date
29/12/2016 10:27
Last modification date
20/08/2019 15:06
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