Langerhans' cell histiocytosis and the nervous system.

Details

Serval ID
serval:BIB_4F38720266A5
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Title
Langerhans' cell histiocytosis and the nervous system.
Journal
Journal of Neurology
Author(s)
Burn D.J., Watson J.D., Roddie M., Chu A.C., Legg N.J., Frackowiak R.S.
ISSN
0340-5354 (Print)
ISSN-L
0340-5354
Publication state
Published
Issued date
1992
Volume
239
Number
6
Pages
345-350
Language
english
Notes
Publication types: Case Reports ; Journal Article ; ReviewPublication Status: ppublish
Abstract
We report two cases of Langerhans' cell histiocytosis with unusual central nervous system (CNS) involvement. The first patient had behavioural disturbances, memory loss and diabetes insipidus. His response to a range of treatments was poor. The second patient presented with seizures and headaches suggestive of raised intracranial pressure. Etoposide (VP16) chemotherapy led to a dramatic clinical and radiological improvement. The various CNS manifestations of Langerhans' cell histiocytosis and their management are discussed.
Keywords
Adult, Central Nervous System Diseases/etiology, Central Nervous System Diseases/radiography, Histiocytosis, Langerhans-Cell/complications, Histiocytosis, Langerhans-Cell/diagnosis, Humans, Male, Tomography, X-Ray Computed
Pubmed
Web of science
Create date
25/09/2011 16:10
Last modification date
20/08/2019 14:04
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