Diffuse large B-cell lymphomas and burkitt lymphoma.

Details

Serval ID
serval:BIB_4EDEEDC17247
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Title
Diffuse large B-cell lymphomas and burkitt lymphoma.
Journal
Hematology/oncology Clinics of North America
Author(s)
de Leval L., Hasserjian R.P.
ISSN
1558-1977[electronic], 0889-8588[linking]
Publication state
Published
Issued date
2009
Volume
23
Number
4
Pages
791-827
Language
english
Abstract
Diffuse large B-cell lymphomas (DLBCLs) and Burkitt lymphoma (BL) account for the majority of aggressive lymphomas in adults and children. DLBCLs exhibit marked biological heterogeneity and variable clinical presentation and clinical course. Conversely, BL is genetically relatively homogeneous but associated with variable clinicopathological features. In this article, the authors summarize the recent advances pertaining to these B-cell neoplasms, following the latest World Health Organization classification and focusing on changes introduced since the previous edition. These changes include the addition of variants and subgroups of DLBCLs and "borderline" categories for high-grade B-cell neoplasms that show features intermediate between DLBCL and classical Hodgkin lymphoma, or between DLBCL and BL. In particular, the diagnostic and therapeutic problems related to neoplasms with features intermediate between DLBCL and BL will be discussed.
Keywords
Adult, Antigens, CD20/immunology, Antigens, CD5/immunology, Burkitt Lymphoma/classification, Burkitt Lymphoma/diagnosis, Child, Diagnosis, Differential, Humans, Immunophenotyping, Lymphoma, Large B-Cell, Diffuse/classification, Lymphoma, Large B-Cell, Diffuse/diagnosis, World Health Organization
Pubmed
Create date
22/10/2010 13:52
Last modification date
20/08/2019 14:04
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