Comparing the self-perceived quality of life of multimorbid patients and the general population using the EQ-5D-3L.

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Version: Final published version
License: CC BY 4.0
Serval ID
serval:BIB_4E0B543D0B8A
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Comparing the self-perceived quality of life of multimorbid patients and the general population using the EQ-5D-3L.
Journal
PloS one
Author(s)
N'Goran A.A., Déruaz-Luyet A., Haller D.M., Zeller A., Rosemann T., Streit S., Herzig L.
ISSN
1932-6203 (Electronic)
ISSN-L
1932-6203
Publication state
Published
Issued date
2017
Peer-reviewed
Oui
Volume
12
Number
12
Pages
e0188499
Language
english
Notes
Publication types: Comparative Study ; Journal Article
Publication Status: epublish
Abstract
To assess and compare the self-perceived Health Related Quality of Life (HRQoL) of multimorbid patients and the general population using health utilities (HU) and visual analogue scale (VAS) methods.
We analyzed data (n = 888) from a national, cross-sectional Swiss study of multimorbid patients recruited in primary care settings. Self-perceived HRQoL was assessed using the EQ-5D-3L instrument, composed of 1) a questionnaire on the five dimensions of mobility, self-care, usual activities, pain/discomfort, and anxiety/depression (EQ-5D dimensions), and 2) a 0-100 (0 = worst- and 100 = best-imaginable health status) VAS. We described the EQ-5D dimensions and VAS and computed HU using a standard pan-European value set. HU and VAS are the two components of the overall HRQoL assessment. We examined the proportions of multimorbid patients reporting problems (moderate/severe) in each EQ-5D dimension, corresponding proportions without problems, and mean HU and VAS values across patient characteristics. To test differences between subgroups, we used chi-square tests for dichotomous outcomes and T-tests (ANOVA if more than two groups) for continuous outcomes. Finally, we compared observed and predicted HU and VAS values.
All 888 participants answered every EQ-5D item. Mean (SD) HU and VAS values were 0.70 (0.18) and 63.2 (19.2), respectively. HU and VAS were considerably and significantly lower in multimorbid patients than in the general population and were also lower in multimorbid patients below 60 years old and in women. Differences between observed and predicted means (SD) were -0.07 (0.18) for HU and -11.8 (20.3) for VAS.
Self-perceived HRQoL is considerably and significantly affected by multimorbidity. More attention should be given to developing interventions that improve the HRQoL of multimorbid patients, particularly women and those aged below 60 years old.

Keywords
Aged, Aged, 80 and over, Comorbidity, Female, Humans, Male, Middle Aged, Quality of Life, Self Concept, Surveys and Questionnaires, Visual Analog Scale
Pubmed
Web of science
Open Access
Yes
Create date
15/01/2018 17:55
Last modification date
20/08/2019 14:03
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