Host genetics: fine-tuning innate signaling.

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Serval ID
serval:BIB_4DC8D32723FC
Type
Article: article from journal or magazin.
Publication sub-type
Editorial
Collection
Publications
Institution
Production externe
Title
Host genetics: fine-tuning innate signaling.
Journal
Current biology
Author(s)
Fellay J., Goldstein D.B.
ISSN
0960-9822 (Print)
ISSN-L
0960-9822
Publication state
Published
Issued date
03/07/2007
Peer-reviewed
Oui
Volume
17
Number
13
Pages
R516-8
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Abstract
A polymorphism modulating innate immunity signal transduction has recently been shown to influence human susceptibility to many different infections, providing one more indication of the potential of host genetics to reveal physiological pathways and mechanisms that influence resistance to infectious diseases.
Keywords
Genetic Predisposition to Disease, Humans, Immunity, Innate/genetics, Membrane Glycoproteins/genetics, Membrane Glycoproteins/immunology, Polymorphism, Single Nucleotide, Receptors, Interleukin-1/genetics, Receptors, Interleukin-1/immunology, Selection, Genetic, Signal Transduction/immunology
DOI
10.1016/j.cub.2007.04.052
Pubmed
17610834
Web of science
000247852100016
Open Access
Yes
Create date
01/03/2012 15:14
Last modification date
27/09/2024 12:49
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