How non-drug interventions affect the quality of life of patients suffering from progressive cognitive decline and their main caregiver.

Details

Serval ID
serval:BIB_4D8137B5A848
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
How non-drug interventions affect the quality of life of patients suffering from progressive cognitive decline and their main caregiver.
Journal
Aging
Author(s)
Leidi-Maimone B., Notter-Bielser M.L., Laouadi M.H., Perrin S., Métraux H., Damian D., Chavan C.F., Nsir M., Cibelli G., Tâche M.J., Montandon M.L., Ghika J., Démonet J.F., Dürst A.V., Guevara A.B.
ISSN
1945-4589 (Electronic)
ISSN-L
1945-4589
Publication state
Published
Issued date
09/06/2020
Peer-reviewed
Oui
Volume
12
Number
11
Pages
10754-10771
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Abstract
In the absence of cure for age-related neurodegenerative diseases, non-drug interventions (NDIs) represent useful options. Quality of life (QOL) is a multidimensional concept progressively affected by cognitive decline. How single or multiple NDIs impact QOL is unknown.
We found no significant effect of multiple over single NDI on QOL. Socio-demographic variables influenced patients' (age, gender, caregivers' occupational status, management of patients' financial affairs) and caregivers' (gender, occupational status, patients' severity of cognitive decline) QOL. When dyads interrupted interventions after 6 months, their QOL was lower and caregivers' anxiety, depression and physical symptoms were higher at the end of the study.
While the type and number of interventions do not appear to be critical, the continuity of adapted interventions in the long-term might be important for maintaining QOL of patients and caregivers.
This is a multicenter (7 Swiss Memory Clinics), quasi-experimental, one-year follow-up study including 148 subjects (mild cognitive impairment or mild dementia patients and their caregivers). Primary outcome was the effect of multiple vs single NDIs on QOL. Secondary outcome included NDIs effect on patients' cognitive impairment and functional autonomy, caregivers' burden, severity of patients' neuropsychiatric symptoms and dyads' anxiety and depression.
Keywords
MCI, caregiver, dementia, non-drug intervention, quality of life
Pubmed
Web of science
Create date
10/06/2020 13:21
Last modification date
15/07/2020 5:26
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