Early pattern recognition in severe perinatal asphyxia: a prospective MRI study.

Details

Serval ID
serval:BIB_4C8D1AE1AECD
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Early pattern recognition in severe perinatal asphyxia: a prospective MRI study.
Journal
Neuroradiology
Author(s)
Baenziger O., Martin E., Steinlin M., Good M., Largo R., Burger R., Fanconi S., Duc G., Buchli R., Rumpel H., Boltshauser R.
ISSN
0028-3940
Publication state
Published
Issued date
1993
Peer-reviewed
Oui
Volume
35
Number
6
Pages
437-42
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't - Publication Status: ppublish
Abstract
On the basis of MRI examinations in 88 neonates and infants with perinatal asphyxia, we defined 6 different patterns on T2-weighted images: pattern A--scattered hyperintensity of both hemispheres of the telencephalon with blurred border zones between cortex and white matter, indicating diffuse brain injury; pattern B--parasagittal hyperintensity extending into the corona radiata, corresponding to the watershed zones; pattern C--hyper- and hypointense lesions in thalamus and basal ganglia, which relate to haemorrhagic necrosis or iron deposition in these areas; pattern D--periventricular hyperintensity, mainly along the lateral ventricles, i.e. periventricular leukomalacia (PVL), originating from the matrix zone; pattern E--small multifocal lesions varying from hyper--to hypointense, interpreted as necrosis and haemorrhage; pattern F--periventricular centrifugal hypointense stripes in the centrum semiovale and deep white matter of the frontal and occipital lobes. Contrast was effectively inverted on T1-weighted images. Patterns A, B and C were found in 17%, 25% and 37% of patients, and patterns D, E and F in 19%, 17% and 35%, respectively. In 49 patients a combination of patterns was observed, but 30% of the initial images were normal. At follow-up, persistent abnormalities were seen in all children with patterns A and D, but in only 52% of those with pattern C. Myelination was retarded most often in patients with diffuse brain injury and PVL (patterns A and D).
Keywords
Asphyxia Neonatorum, Brain, Brain Damage, Chronic, Cerebral Hemorrhage, Female, Follow-Up Studies, Humans, Hypoxia, Brain, Infant, Newborn, Infant, Premature, Diseases, Leukomalacia, Periventricular, Magnetic Resonance Imaging, Male, Pregnancy, Prospective Studies
Pubmed
Web of science
Create date
25/01/2008 10:06
Last modification date
20/08/2019 14:01
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