Outcome measures in spinal cord injury: recent assessments and recommendations for future directions.

Details

Serval ID
serval:BIB_4BEAEA16F357
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Title
Outcome measures in spinal cord injury: recent assessments and recommendations for future directions.
Journal
Spinal Cord
Author(s)
Alexander M.S., Anderson K.D., Biering-Sorensen F., Blight A.R., Brannon R., Bryce T.N., Creasey G., Catz A., Curt A., Donovan W., Ditunno J., Ellaway P., Finnerup N.B., Graves D.E., Haynes B.A., Heinemann A.W., Jackson A.B., Johnston M.V., Kalpakjian C.Z., Kleitman N., Krassioukov A., Krogh K., Lammertse D., Magasi S., Mulcahey M.J., Schurch B., Sherwood A., Steeves J.D., Stiens S., Tulsky D.S., van Hedel H.J., Whiteneck G.
ISSN
1476-5624 (Electronic)
ISSN-L
1362-4393
Publication state
Published
Issued date
2009
Volume
47
Number
8
Pages
582-591
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't ; ReviewPublication Status: ppublish
Abstract
STUDY DESIGN: Review by the spinal cord outcomes partnership endeavor (SCOPE), which is a broad-based international consortium of scientists and clinical researchers representing academic institutions, industry, government agencies, not-for-profit organizations and foundations.
OBJECTIVES: Assessment of current and evolving tools for evaluating human spinal cord injury (SCI) outcomes for both clinical diagnosis and clinical research studies.
METHODS: a framework for the appraisal of evidence of metric properties was used to examine outcome tools or tests for accuracy, sensitivity, reliability and validity for human SCI.
RESULTS: Imaging, neurological, functional, autonomic, sexual health, bladder/bowel, pain and psychosocial tools were evaluated. Several specific tools for human SCI studies have or are being developed to allow the more accurate determination for a clinically meaningful benefit (improvement in functional outcome or quality of life) being achieved as a result of a therapeutic intervention.
CONCLUSION: Significant progress has been made, but further validation studies are required to identify the most appropriate tools for specific targets in a human SCI study or clinical trial.
Keywords
Clinical Trials as Topic/methods, Clinical Trials as Topic/standards, Humans, Outcome Assessment (Health Care)/methods, Outcome Assessment (Health Care)/standards, Spinal Cord Injuries/diagnosis, Spinal Cord Injuries/therapy, Treatment Outcome
Pubmed
Web of science
Open Access
Yes
Create date
05/11/2014 12:13
Last modification date
20/08/2019 14:00
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