Anticoagulation régionale au citrate pour l’épuration extrarénale continue [Regional citrate anticoagulation for continuous renal replacement therapy]

Details

Serval ID
serval:BIB_4B7E90352BE4
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Anticoagulation régionale au citrate pour l’épuration extrarénale continue [Regional citrate anticoagulation for continuous renal replacement therapy]
Journal
Revue medicale suisse
Author(s)
Bezençon E., Ferlay C., Alouazem K., Plouhinec V., Schneider A.G.
ISSN
1660-9379 (Print)
ISSN-L
1660-9379
Publication state
Published
Issued date
21/10/2020
Peer-reviewed
Oui
Volume
16
Number
711
Pages
2002-2006
Language
french
Notes
Publication types: English Abstract ; Journal Article
Publication Status: ppublish
Abstract
Regional citrate anticoagulation (RCA) is currently the recommended anticoagulation modality for continuous renal replacement therapy. Indeed, compared with systemic heparinization, RCA is associated with a lower risk of bleeding, a longer circuit lifespan and a decrease nursing workload. However, RCA requires a strict protocol to be followed, as it might be associated with potentially severe complications, such as citrate accumulation. Citrate accumulation is rare and usually associated with specific situations : severe circulatory shock, liver failure and mitochondrial dysfunction. According to centers' expertise, these situations might represent contra-indications to RCA. This review presents RCA, its mode of action, associated risks and proposes an algorithm for patients' selection.
Pubmed
Create date
26/10/2020 14:30
Last modification date
20/01/2021 7:26
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