Chirurgie iterative en cas de tumeur germinale. [Iterative surgery in germ cell tumor]

Details

Serval ID
serval:BIB_4B675721CCF5
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Chirurgie iterative en cas de tumeur germinale. [Iterative surgery in germ cell tumor]
Journal
Helvetica Chirurgica Acta
Author(s)
Merlini  M., Boumghar  M., Berner  M., Leyvraz  S., Chapuis  G.
ISSN
0018-0181 (Print)
Publication state
Published
Issued date
01/1989
Volume
55
Number
5
Pages
549-52
Notes
English Abstract
Journal Article --- Old month value: Jan
Abstract
Between 1979 and 1988, iterative surgery was performed on 13 patients for a germ-cell tumor. Apart from orchidectomy, surgery was not the first modality of treatment. On the other hand, 21 surgical procedures were performed for residual tumoral masses after chemotherapy or recurrences. In one third of the cases, only necrosis of fibrosis was resected. Out of 13 patients, 7 died of tumor; 6 are alive (3 with complete remission). Surgery is always indicated in stage IIA to IV nonseminomatous tumors in case of residual tumoral deposits after chemotherapy. For seminoma, surgery is carried out only for retroperitoneal residues larger than 3 cm in diameter. Surgery is also indicated for persistent pulmonary or mediastinal metastases following chemotherapy. Complete surgical excision of residual masses may be technically difficult but is of prime importance as combined chemotherapy and surgery doubles the complete remission rate in comparison to chemotherapy alone.
Keywords
Combined Modality Therapy Follow-Up Studies Humans Male Mediastinal Neoplasms/*surgery Neoplasms, Germ Cell and Embryonal/*surgery Retroperitoneal Neoplasms/*surgery Testicular Neoplasms/*surgery
Pubmed
Web of science
Create date
28/01/2008 9:32
Last modification date
20/08/2019 14:59
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