Postmortem Internal Gas Reservoir Monitoring Using GC×GC-HRTOF-MS

Details

Ressource 1Download: wos000385575100004.pdf (2506.33 [Ko])
State: Public
Version: Final published version
Serval ID
serval:BIB_4A8F4C595026
Type
Article: article from journal or magazin.
Collection
Publications
Title
Postmortem Internal Gas Reservoir Monitoring Using GC×GC-HRTOF-MS
Journal
Separations
Author(s)
Stefanuto Pierre-Hugues, Perrault Katelynn, Grabherr Silke, Varlet Vincent, Focant Jean-François
ISSN
2297-8739
ISSN-L
2297-8739
Publication state
Published
Issued date
17/08/2016
Peer-reviewed
Oui
Volume
3
Number
3
Pages
24
Language
english
Abstract
Forensic investigations often require postmortem examination of a body. However, the collection of evidence during autopsy is often destructive, meaning that the body can no longer be examined in its original state. In order to obtain an internal image of the body, whole body postmortem computed tomography (PMCT) has proven to be a valuable non-destructive tool and is currently used in medicolegal centers. PMCT can also be used to visually locate gas reservoirs inside a cadaver, which upon analysis can provide useful information regarding very volatile compounds that are produced after death. However, the non-targeted profiling of all potential volatile organic compounds (VOCs) present in these reservoirs has never been attempted. The aim of this study was to investigate the VOC profile of these reservoirs and to evaluate potential uses of such information to document circumstances surrounding death, cause of death and body taphonomy. Comprehensive two-dimensional gas chromatography coupled to time-of-flight high-resolution mass spectrometry (GCxGC-HRTOF-MS) was used for VOC measurements. This study demonstrated that the chemical composition of VOCs within the gas reservoirs differed between locations within a single body but also between individuals. In the future, this work could be expanded to investigate a novel, non-destructive cadaver screening approach prior to full autopsy procedures.
Keywords
human decomposition, forensic chemistry, comprehensive two-dimensional gas chromatography coupled to time-of-flight high-resolution mass spectrometry (GCxGC-HRTOF-MS), volatile organic compounds, multivariate statistics
Web of science
Open Access
Yes
Create date
29/11/2016 12:25
Last modification date
20/08/2019 14:58
Usage data