Human angiotensin I competes with two non-thiol converting enzyme inhibitors (CGS 13934 & MK-422) to inhibit the angiotensin-converting enzyme activity of human plasma

Details

Serval ID
serval:BIB_4A579A6DC19A
Type
Article: article from journal or magazin.
Collection
Publications
Title
Human angiotensin I competes with two non-thiol converting enzyme inhibitors (CGS 13934 & MK-422) to inhibit the angiotensin-converting enzyme activity of human plasma
Journal
Journal of Pharmacy and Pharmacology
Author(s)
Chen  D. S., Nussberger  J., Brunner  H. R., Waeber  B.
ISSN
0022-3573 (Print)
Publication state
Published
Issued date
10/1984
Volume
36
Number
10
Pages
707-8
Notes
In Vitro
Journal Article
Research Support, Non-U.S. Gov't --- Old month value: Oct
Abstract
A simple in-vitro enzyme system has been used to demonstrate that human angiotensin I interacts competitively with the two non-thiol converting enzyme inhibitors CGS 13934 and MK-422 to inhibit the hydrolysis of a synthetic substrate by human plasma ACE.
Keywords
Angiotensin I/*pharmacology *Angiotensin-Converting Enzyme Inhibitors Angiotensins/*pharmacology Dipeptides/*pharmacology Enalaprilat Female Humans Indoles/*pharmacology Kinetics Male Peptidyl-Dipeptidase A/blood
Pubmed
Web of science
Create date
05/03/2008 16:39
Last modification date
20/08/2019 13:58
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