Predictive accuracy and usefulness of calibration of the ESC SCORE in Switzerland.

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State: Public
Version: author
Serval ID
serval:BIB_49974905D96F
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Predictive accuracy and usefulness of calibration of the ESC SCORE in Switzerland.
Journal
European Journal of Cardiovascular Prevention and Rehabilitation
Author(s)
Marques-Vidal P., Rodondi N., Bochud M., Pécoud A., Hayoz D., Paccaud F., Mooser V., Waeber G., Vollenweider P.
ISSN
1741-8267
ISSN-L
1741-8267
Publication state
Published
Issued date
2008
Peer-reviewed
Oui
Volume
15
Number
4
Pages
402-408
Language
english
Abstract
BACKGROUND: Prevention of cardiovascular disease (CVD) at the individual level should rely on the assessment of absolute risk using population-specific risk tables. OBJECTIVE: To compare the predictive accuracy of the original and the calibrated SCORE functions regarding 10-year cardiovascular risk in Switzerland. DESIGN: Cross-sectional, population-based study (5773 participants aged 35-74 years). METHODS: The SCORE equation for low-risk countries was calibrated based on the Swiss CVD mortality rates and on the CVD risk factor levels from the study sample. The predicted number of CVD deaths after a 10-year period was computed from the original and the calibrated equations and from the observed cardiovascular mortality for 2003. RESULTS: According to the original and calibrated functions, 16.3 and 15.8% of men and 8.2 and 8.9% of women, respectively, had a 10-year CVD risk > or =5%. Concordance correlation coefficient between the two functions was 0.951 for men and 0.948 for women, both P<0.001. Both risk functions adequately predicted the 10-year cumulative number of CVD deaths: in men, 71 (original) and 74 (calibrated) deaths for 73 deaths when using the CVD mortality rates; in women, 44 (original), 45 (calibrated) and 45 (CVD mortality rates), respectively. Compared to the original function, the calibrated function classified more women and fewer men at high-risk. Moreover, the calibrated function gave better risk estimates among participants aged over 65 years. CONCLUSION: The original SCORE function adequately predicts CVD death in Switzerland, particularly for individuals aged less than 65 years. The calibrated function provides more reliable estimates for older individuals.
Keywords
Adult, Aged, Blood Pressure, Cardiovascular Diseases, Female, Humans, Male, Middle Aged, Models, Statistical, Risk Assessment, Risk Factors, Switzerland , Colaus Study
Pubmed
Web of science
Create date
10/03/2009 8:45
Last modification date
20/08/2019 14:57
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