Hearing and saying. The functional neuro-anatomy of auditory word processing.

Details

Serval ID
serval:BIB_48B6CB10931B
Type
Article: article from journal or magazin.
Collection
Publications
Title
Hearing and saying. The functional neuro-anatomy of auditory word processing.
Journal
Brain
Author(s)
Price C.J., Wise R.J., Warburton E.A., Moore C.J., Howard D., Patterson K., Frackowiak R.S., Friston K.J.
ISSN
0006-8950 (Print)
ISSN-L
0006-8950
Publication state
Published
Issued date
1996
Volume
119 ( Pt 3)
Pages
919-931
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov'tPublication Status: ppublish
Abstract
The neural systems involved in hearing and repeating single words were investigated in a series of experiments using PET. Neuropsychological and psycholinguistic studies implicate the involvement of posterior and anterior left perisylvian regions (Wernicke's and Broca's areas). Although previous functional neuroimaging studies have consistently shown activation of Wernicke's area, there has been only variable implication of Broca's area. This study demonstrates that Broca's area is involved in both auditory word perception and repetition but activation is dependent on task (greater during repetition than hearing) and stimulus presentation (greater when hearing words at a slow rate). The peak of frontal activation in response to hearing words is anterior to that associated with repeating words; the former is probably located in Brodmann's area 45, the latter in Brodmann's area 44 and the adjacent precentral sulcus. As Broca's area activation is more subtle and complex than that in Wernicke's area during these tasks, the likelihood of observing it is influenced by both the study design and the image analysis technique employed. As a secondary outcome from the study, the response of bilateral auditory association cortex to 'own voice' during repetition was shown to be the same as when listening to "other voice' from a prerecorded tape.
Keywords
Auditory Perception/physiology, Brain Mapping, Cerebellum/anatomy & histology, Cerebellum/physiology, Frontal Lobe/anatomy & histology, Frontal Lobe/physiology, Hearing/physiology, Humans, Motor Cortex/anatomy & histology, Motor Cortex/physiology, Somatosensory Cortex/anatomy & histology, Somatosensory Cortex/physiology, Speech/physiology, Tomography, Emission-Computed
Pubmed
Web of science
Open Access
Yes
Create date
16/09/2011 18:48
Last modification date
20/08/2019 13:55
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