Prevention of major depression in complex medically ill patients: preliminary results from a randomized, controlled trial.

Details

Serval ID
serval:BIB_48A1B1B535A2
Type
Article: article from journal or magazin.
Collection
Publications
Title
Prevention of major depression in complex medically ill patients: preliminary results from a randomized, controlled trial.
Journal
Psychosomatics
Author(s)
de Jonge P., Hadj F.B., Boffa D., Zdrojewski C., Dorogi Y., So A., Ruiz J., Stiefel F.
ISSN
1545-7206[electronic]
Publication state
Published
Issued date
2009
Peer-reviewed
Oui
Volume
50
Number
3
Pages
227-33
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't - Publication Status: ppublish
Abstract
BACKGROUND: Depression is highly prevalent in patients with physical illness and is associated with a diminished quality of life and poorer medical outcomes. OBJECTIVE: The authors evaluated whether a multifaceted intervention conducted by a psychiatric consultation-liaison nurse could reduce the incidence of major depression in rheumatology inpatients and diabetes outpatients with a high level of case complexity. METHOD: Of 247 randomized patients, the authors identified 100 patients with a high level of case complexity at baseline and without major depression (65 rheumatology and 35 diabetes patients). Patients were randomized to usual care (N=53) or to a nurse-led intervention (N=47). Main outcomes were the incidence of major depression and severity of depressive symptoms during a 1-year follow-up, based on quarterly assessments with standardized psychiatric interviews. RESULTS: The incidence of major depression was 63% in usual-care patients and 36% in the intervention group. Effects of intervention on depressive symptoms were observed in outpatients with diabetes but not in rheumatology inpatients. CONCLUSION: These preliminary results based on subgroup analysis suggest that a multifaceted nurse-led intervention may prevent the occurrence of major depression in complex medically ill patients and reduce depressive symptoms in diabetes outpatients.
Pubmed
Web of science
Create date
09/07/2009 13:44
Last modification date
20/08/2019 13:55
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