Increased striatal gray matter densities in patients with schizophrenia and substance use disorder : a voxel-based morphometry study
Details
Serval ID
serval:BIB_48238860B070
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Increased striatal gray matter densities in patients with schizophrenia and substance use disorder : a voxel-based morphometry study
Journal
Psychiatry research
ISSN
0165-1781
Publication state
Published
Issued date
2007
Volume
154
Number
3
Pages
275-9
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't - Publication Status: ppublish
Abstract
We sought to investigate the link between substance abuse and increased striatal gray matter densities (GMD) in schizophrenia, using voxel-based morphometry (VBM). Increased striatal GMD were found in patients with schizophrenia and substance use disorder (n=12), but not schizophrenia only patients (n=11), compared to healthy volunteers (n=15).
Keywords
Adult, Antipsychotic Agents / pharmacology, Antipsychotic Agents / therapeutic use, Cell Count, Corpus Striatum / drug effects, Corpus Striatum / pathology, Diagnostic and Statistical Manual of Mental Disorders, Female, Haloperidol / pharmacology, Haloperidol / therapeutic use, Humans, Magnetic Resonance Spectroscopy, Male, Receptors, Dopamine D2 / drug effects, Schizophrenia / drug therapy, Schizophrenia / epidemiology, Severity of Illness Index, Substance-Related Disorders / diagnosis, Substance-Related Disorders / epidemiology
Pubmed
Create date
24/06/2009 14:38
Last modification date
20/08/2019 14:54
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