Intracranial aneurysm coiling with PGLA-coated coils versus bare platinum coils: long-term anatomic follow-up.
Details
Serval ID
serval:BIB_48149FDA30C5
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Intracranial aneurysm coiling with PGLA-coated coils versus bare platinum coils: long-term anatomic follow-up.
Journal
Neuroradiology
ISSN
1432-1920 (Electronic)
ISSN-L
0028-3940
Publication state
Published
Issued date
04/2012
Peer-reviewed
Oui
Volume
54
Number
4
Pages
345-348
Language
english
Notes
Publication types: Comparative Study ; Journal Article
Publication Status: ppublish
Publication Status: ppublish
Abstract
The purpose of this study is to compare the long-term (≥12 months) angiographic follow-up of aneurysms treated with polymer polyglycolic-lactic acid (PGLA)-coated coils versus bare platinum coils.
Long-term angiographic follow-up results of 90 aneurysms treated exclusively with PGLA-coated coils were retrospectively analyzed and compared to those of 158 aneurysms treated exclusively with bare platinum coils.
There were 32 ruptured aneurysms (35.5%) in the PGLA-coated coil group and 62 (39.2%) in the bare platinum coil group. The mean angiographic follow-up was 29 months in the PGLA-coated coil group versus 27 months in the bare platinum coil group (P = 0.2297). The mean time to angiographic recurrence was 14 months in the PGLA-coated coil group versus 18 months in the bare platinum coil group (P = 0.1088). Recurrence rates were 35.6% (32/90) and 31.0% (49/158) in the PGLA-coated coil and bare platinum coil groups, respectively (P = 0.4837). The major recurrence justifying retreatment was 5.6% (5/90) in the PGLA-coated coil group versus 6.7% (10/158) in the bare platinum coil group (P = 1.000).
PGLA-coated coils provided no better long-term recanalization rates than bare platinum coils.
Long-term angiographic follow-up results of 90 aneurysms treated exclusively with PGLA-coated coils were retrospectively analyzed and compared to those of 158 aneurysms treated exclusively with bare platinum coils.
There were 32 ruptured aneurysms (35.5%) in the PGLA-coated coil group and 62 (39.2%) in the bare platinum coil group. The mean angiographic follow-up was 29 months in the PGLA-coated coil group versus 27 months in the bare platinum coil group (P = 0.2297). The mean time to angiographic recurrence was 14 months in the PGLA-coated coil group versus 18 months in the bare platinum coil group (P = 0.1088). Recurrence rates were 35.6% (32/90) and 31.0% (49/158) in the PGLA-coated coil and bare platinum coil groups, respectively (P = 0.4837). The major recurrence justifying retreatment was 5.6% (5/90) in the PGLA-coated coil group versus 6.7% (10/158) in the bare platinum coil group (P = 1.000).
PGLA-coated coils provided no better long-term recanalization rates than bare platinum coils.
Keywords
Aneurysm, Ruptured/diagnostic imaging, Aneurysm, Ruptured/therapy, Cerebral Angiography, Coated Materials, Biocompatible, Embolization, Therapeutic/instrumentation, Female, Follow-Up Studies, Humans, Intracranial Aneurysm/diagnostic imaging, Intracranial Aneurysm/therapy, Logistic Models, Male, Middle Aged, Platinum, Polyglycolic Acid, Radiography, Interventional, Recurrence, Retrospective Studies, Statistics, Nonparametric, Treatment Outcome
Pubmed
Create date
03/05/2017 11:44
Last modification date
23/02/2024 14:15
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