Hemophagocytic Lymphohistiocytosis and Gastrointestinal Bleeding: What a Surgeon Should Know

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Ressource 1Download: BIB_46A59706E382.P001.pdf (944.47 [Ko])
State: Public
Version: Final published version
Serval ID
serval:BIB_46A59706E382
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Institution
Title
Hemophagocytic Lymphohistiocytosis and Gastrointestinal Bleeding: What a Surgeon Should Know
Journal
Case Reports In Surgery
Author(s)
Popeskou S., Gavillet M., Demartines N., Christoforidis D.
ISSN
2090-6900 (Print)
2090-6919 (Electronic)
Publication state
Published
Issued date
2015
Peer-reviewed
Oui
Volume
2015
Pages
745848
Language
english
Notes
Publication types: Case Report ; case-report Identifiant PubMed Central: PMC4496477
Abstract
This paper presents to the surgical community an unusual and often ignored cause of gastrointestinal bleeding. Hemophagocytic syndrome or hemophagocytic lymphohistiocytosis (HLH) is a rare medical entity characterized by phagocytosis of red blood cells, leucocytes, platelets, and their precursors in the bone marrow by activated macrophages. When intestinal bleeding is present, the management is very challenging with extremely high mortality rates. Early diagnosis and treatment seem to be the most important factors for a successful outcome. We present two cases and review another 18 from the literature.
Pubmed
Open Access
Yes
Create date
25/07/2016 9:19
Last modification date
20/08/2019 14:52
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