New York Heart Association class versus amino-terminal pro-B type natriuretic peptide for acute heart failure prognosis.
Details
Serval ID
serval:BIB_45AB125CC466
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
New York Heart Association class versus amino-terminal pro-B type natriuretic peptide for acute heart failure prognosis.
Journal
Biomarkers
ISSN
1366-5804 (Electronic)
ISSN-L
1354-750X
Publication state
Published
Issued date
06/2010
Peer-reviewed
Oui
Volume
15
Number
4
Pages
307-314
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Publication Status: ppublish
Abstract
The prognostic value of the New York Heart Association classification (NYHAC) in acutely decompensated heart failure (ADHF) is unknown.
We sought to determine the relative value of NYHAC among patients with concomitantly measured amino-terminal pro-B type natriuretic peptide (NT-proBNP) at presentation with ADHF.
NYHAC was determined for 720 patients with ADHF and 1-year mortality status was examined. Cox-proportional hazards analysis compared the prognostic accuracy of NYHAC with other ADHF risk measures.
NYHAC had a significant univariate association with 1-year mortality status (HR 1.41, 95% confidence interval (CI) 1.03-1.94; p = 0.03) but was not a significant predictor of death in a multivariable model that included NT-proBNP (HR 2.14; 95% CI 1.65-2.81, p < 0.001).
In contrast to objective measures such as NT-proBNP, the NYHAC appears to provide limited prognostic information among individuals with ADHF.
We sought to determine the relative value of NYHAC among patients with concomitantly measured amino-terminal pro-B type natriuretic peptide (NT-proBNP) at presentation with ADHF.
NYHAC was determined for 720 patients with ADHF and 1-year mortality status was examined. Cox-proportional hazards analysis compared the prognostic accuracy of NYHAC with other ADHF risk measures.
NYHAC had a significant univariate association with 1-year mortality status (HR 1.41, 95% confidence interval (CI) 1.03-1.94; p = 0.03) but was not a significant predictor of death in a multivariable model that included NT-proBNP (HR 2.14; 95% CI 1.65-2.81, p < 0.001).
In contrast to objective measures such as NT-proBNP, the NYHAC appears to provide limited prognostic information among individuals with ADHF.
Keywords
Acute Disease, Aged, Aged, 80 and over, Female, Heart Failure/classification, Heart Failure/diagnosis, Heart Failure/mortality, Humans, Male, Middle Aged, Natriuretic Peptide, Brain/blood, New York, Patient Selection, Peptide Fragments/blood, Predictive Value of Tests, Ventricular Function, Left
Pubmed
Web of science
Create date
07/12/2022 12:02
Last modification date
12/03/2025 8:08
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