Postmortem biochemistry performed on vitreous humor after postmortem CT-angiography.

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State: Public
Version: author
Serval ID
serval:BIB_4498F4296A38
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Postmortem biochemistry performed on vitreous humor after postmortem CT-angiography.
Journal
Legal Medicine
Author(s)
Grabherr S., Widmer C., Iglesias K., Sporkert F., Augsburger M., Mangin P., Palmiere C.
ISSN
1873-4162 (Electronic)
ISSN-L
1344-6223
Publication state
Published
Issued date
2012
Peer-reviewed
Oui
Volume
14
Number
6
Pages
297-303
Language
english
Notes
Publication types: Journal Article
Abstract
Postmortem angiography is becoming increasingly essential in forensic pathology as an adjunct to conventional autopsy. Despite the numerous advantages of this technique, some questions have been raised regarding the influence of the contrast agent injected on the results of toxicological and biochemical analyses. The aim of this study was to investigate the effect of the injection of the contrast agent Angiofil®, mixed with paraffin oil, on the results of postmortem biochemical investigations performed on vitreous humor. Postmortem biochemical investigations were performed on vitreous samples collected from bodies that had undergone postmortem angiography (n=50) and from a control group (n=50). Two vitreous samples were analyzed for each group and the results compared. Glucose, urea, creatinine, 3-β-hydroxybutyrate, sodium and chloride were tested. Different values were observed between the first and second samples in each group. However, these differences were not clinically relevant, suggesting that the injection of this contrast agent mixture does not modify the concentration of the analyzed substances in the vitreous humor.
Keywords
Angiography/methods, Autopsy/methods, Biochemistry/methods, Contrast Media/analysis, Female, Forensic Pathology/methods, Humans, Male, Middle Aged, Vitreous Body/chemistry
Pubmed
Web of science
Create date
15/11/2012 19:20
Last modification date
20/08/2019 14:49
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