The International Database of Central Arterial Properties for Risk Stratification: Research Objectives and Baseline Characteristics of Participants.

Details

Serval ID
serval:BIB_44535176CF64
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
The International Database of Central Arterial Properties for Risk Stratification: Research Objectives and Baseline Characteristics of Participants.
Journal
American journal of hypertension
Author(s)
Aparicio L.S., Huang Q.F., Melgarejo J.D., Wei D.M., Thijs L., Wei F.F., Gilis-Malinowska N., Sheng C.S., Boggia J., Niiranen T.J., Odili A.N., Stolarz-Skrzypek K., Barochiner J., Ackermann D., Kawecka-Jaszcz K., Tikhonoff V., Zhang Z.Y., Casiglia E., Narkiewicz K., Filipovský J., Schutte A.E., Yang W.Y., Jula A.M., Woodiwiss A.J., Bochud M., Norton G.R., Wang J.G., Li Y., Staessen J.A.
Working group(s)
International Database of Central Arterial Properties for Risk Stratification (IDCARS) Investigators
Contributor(s)
Aparicio L.S., Barochiner J., Wei D.M., Melgarejo J.D., Thijs L., Staessen J.A., Wei F.F., Yang W.Y., Zhang Z.Y., An D.W., Cheng Y.B., Guo Q.H., Huang J.F., Huang Q.F., Li Y., Sheng C.S., Wang J.G., Filipovský J., Seidlerová J., Juhanoja E.P., Jula A.M., Lindroos A.S., Niiranen T.J., Sivén S.S., Casiglia E., Pizzioli A., Tikhonoff V., Chori B.S., Danladi B., Odili A.N., Oshaju H., Kucharska W., Kunicka K., Gilis-Malinowska N., Narkiewicz K., Sakiewicz W., Swierblewska E., Kawecka-Jaszcz K., Stolarz-Skrzypek K., Rajzer M., Mels C., Kruger R., Mokwatsi G., Schutte A.E., Norton G.R., Woodiwiss A.J., Ackermann D., Bochud M., Ehret G., Álvarez-Vaz R., Américo C., Baccino C., Borgarello L., Florio L., Moliterno P., Noboa A., Noboa O., Olascoaga A., Parnizari P., Pécora M.
ISSN
1941-7225 (Electronic)
ISSN-L
0895-7061
Publication state
Published
Issued date
05/01/2022
Peer-reviewed
Oui
Volume
35
Number
1
Pages
54-64
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Abstract
To address to what extent central hemodynamic measurements, improve risk stratification, and determine outcome-based diagnostic thresholds, we constructed the International Database of Central Arterial Properties for Risk Stratification (IDCARS), allowing a participant-level meta-analysis. The purpose of this article was to describe the characteristics of IDCARS participants and to highlight research perspectives.
Longitudinal or cross-sectional cohort studies with central blood pressure measured with the SphygmoCor devices and software were included.
The database included 10,930 subjects (54.8% women; median age 46.0 years) from 13 studies in Europe, Africa, Asia, and South America. The prevalence of office hypertension was 4,446 (40.1%), of which 2,713 (61.0%) were treated, and of diabetes mellitus was 629 (5.8%). The peripheral and central systolic/diastolic blood pressure averaged 129.5/78.7 mm Hg and 118.2/79.7 mm Hg, respectively. Mean aortic pulse wave velocity was 7.3 m per seconds. Among 6,871 participants enrolled in 9 longitudinal studies, the median follow-up was 4.2 years (5th-95th percentile interval, 1.3-12.2 years). During 38,957 person-years of follow-up, 339 participants experienced a composite cardiovascular event and 212 died, 67 of cardiovascular disease.
IDCARS will provide a unique opportunity to investigate hypotheses on central hemodynamic measurements that could not reliably be studied in individual studies. The results of these analyses might inform guidelines and be of help to clinicians involved in the management of patients with suspected or established hypertension.
Keywords
Cardiovascular outcome, central blood pressure, hemodynamics, pulse wave analysis, pulse wave velocity, blood pressure, cardiovascular outcome, hypertension
Pubmed
Web of science
Open Access
Yes
Create date
21/09/2021 13:49
Last modification date
22/04/2022 6:37
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