Motor overactivity and loss of motor circadian rhythm in fatal familial insomnia: an actigraphic study.

Details

Serval ID
serval:BIB_443ED03E15F2
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Institution
Title
Motor overactivity and loss of motor circadian rhythm in fatal familial insomnia: an actigraphic study.
Journal
Sleep
Author(s)
Plazzi G., Schutz Y., Cortelli P., Provini F., Avoni P., Heikkila E., Tinuper P., Solieri L., Lugaresi E., Montagna P.
ISSN
0161-8105 (Print)
ISSN-L
0161-8105
Publication state
Published
Issued date
09/1997
Volume
20
Number
9
Pages
739-742
Language
english
Notes
Publication types: Case Reports ; Comparative Study ; Journal Article
Publication Status: ppublish
Abstract
The 24-hour rest-activity pattern and the amount of motor activity was studied in a patient with fatal familial insomnia (FFI) by means of wrist actigraphy. During the study, the patient underwent indirect calorimetry. The 52-day recording showed severe disruption of the 24-hour rest-activity pattern with increased motor activity up to 80%. The 24-hour energy expenditure, assayed in a respiration chamber, was strikingly elevated by 60%. Chronic motor overactivity and loss of circadian rest-activity rhythm may play a role in the progressive metabolic exhaustion leading to death in FFI patients.
Keywords
Body Mass Index, Calorimetry, Indirect, Circadian Rhythm, Energy Intake, Fatal Outcome, Humans, Hyperkinesis/etiology, Male, Middle Aged, Sleep Initiation and Maintenance Disorders/complications, Sleep Initiation and Maintenance Disorders/diagnosis
Pubmed
Web of science
Create date
21/01/2008 13:09
Last modification date
20/08/2019 13:48
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